Dioxolane is being widely accepted in waterborne coatings formulation, due to its high solvency and water solubility.
These calculations aimed at determination of relative thermodynamic stability of cyclic acetals of different types-dioxepanes, dioxanes, and
dioxolanes. It was found that
dioxolane 8 and dioxane 9 were less stable than dioxepane 3.
Inhibitory activity of
dioxolane purine analogs on wild-type and lamivudine-resistant mutants of hepadnaviruses.
Pt [(acac) .sub.2] in PDMS-V MH-PDMS TEOS
dioxolane Water Triethylamine Step 1 0.86 / O.X / / / Water / / / / 10 0.2 Solution Step 2 / 0.14 / 0.02 / / TABLE 2.
Their topics include the chemical synthesis of acyclic nucleosides, mononucleotide pro-drug synthetic strategies, synthesizing conformally constrained nucleoside analogues, stereoselective methods in synthesizing bioactive oxathiolate and
dioxolane nucleosides, and synthetic studies on antifungal peptidyl nucleoside antibiotics.
Dioxolane guanosine 5'-triphosphate, an alternative substrate inhibitor of wild-type and mutant HIV-1 reverse transcriptase.
My last remuneration for a drug study was more than 45 years ago, when I tested a combination of
dioxolane and reserpine.
Our new "DOI"
dioxolane based (meth)acrylates offer low skin irritation and unique properties.
(Laval, Canada) has patented a process for stereoselectively producing a
dioxolane nucleoside analogue from an anomeric mixture of .beta.
Dimers of gA can be obtained by introduction of a
dioxolane ring between N-formylated termini of two gA molecules.
A second drug in this class is amdoxovir (also called diaminopurine
dioxolane or DAPD).
A guanosine analog from the class of nucleoside analogs, (-)-[beta]-D-2,6-diaminopurine
dioxolane showed activity in vitro against resistant viral isolates in phase I and II studies to be presented in early 2000.