dioxolane


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dioxolane

[dī′äk·sə‚lān]
(organic chemistry)
C3H6O2 A cyclic acetal that is a liquid; used as a solvent and extractant.
References in periodicals archive ?
Inhibitory activity of dioxolane purine analogs on wild-type and lamivudine-resistant mutants of hepadnaviruses.
Their topics include the chemical synthesis of acyclic nucleosides, mononucleotide pro-drug synthetic strategies, synthesizing conformally constrained nucleoside analogues, stereoselective methods in synthesizing bioactive oxathiolate and dioxolane nucleosides, and synthetic studies on antifungal peptidyl nucleoside antibiotics.
Dioxolane guanosine 5'-triphosphate, an alternative substrate inhibitor of wild-type and mutant HIV-1 reverse transcriptase.
My last remuneration for a drug study was more than 45 years ago, when I tested a combination of dioxolane and reserpine.
Our new "DOI" dioxolane based (meth)acrylates offer low skin irritation and unique properties.
Laval, Canada) has patented a process for stereoselectively producing a dioxolane nucleoside analogue from an anomeric mixture of .
Dimers of gA can be obtained by introduction of a dioxolane ring between N-formylated termini of two gA molecules.
A second drug in this class is amdoxovir (also called diaminopurine dioxolane or DAPD).
A guanosine analog from the class of nucleoside analogs, (-)-[beta]-D-2,6-diaminopurine dioxolane showed activity in vitro against resistant viral isolates in phase I and II studies to be presented in early 2000.
Seebach discussed the catalytic use of similar complexes derived from tetraaryl dioxolane dimethanols (TADDOLs) and tetraisopropoxy titanium to mediate asymmetric addition of organozinc compounds to compounds such as saturated and unsaturates aldehydes.