Dipeptides


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Dipeptides

 

organic substances consisting of two amino acids connected by a peptide bond (—CO—NH—). Optically active, they form crystals of characteristic shape. The isoelectric point, color reactions, and other properties of dipeptides are determined by the amino acids that enter into their composition. Dipeptides are compounds intermediate between polypeptides and amino acids and are formed by the hydrolysis of proteins. Dipeptides consisting of the same L-amino acids but in different order yield isomers, for example, leucyl-alanine and alanyl-leucine. Natural dipeptides, such as carnosine and anserine, are found in animal tissues. A dipeptide molecule can be hydrolyzed by acids, alkalies, or enzymes (dipeptidases) to yield two amino acids.

References in periodicals archive ?
The generation of amino acids and dipeptides also contributes to the improvement of beef flavor.
These overrepresented classes covered over half (33/53) of the metabolites in the five annotated lipid pathways; half (3/6) of the metabolites in the purine metabolism, (hypo)xanthine/inosine-containing pathway; and over a third (24/61) of the metabolites on the dipeptide pathway.
Purification and identification of a novel primitive secretory enzyme catalyzing the hydrolysis of imidazole-related dipeptides in the jawless vertebrate Lethenteron reissneri.
The potentially rapid turnover of dipeptides necessitates appropriate soil sampling methodology, avoiding disturbances that can cause artefacts, such as microbial ON consumption, enzymatic ON degradation and leakage of ON and proteases from soil organisms and roots.
Fresh solutions of the aqua derivatives of dinuclear platinum(II) complexes la-3a and Ac-L-Met-Gly and Ac-L-His-Gly dipeptides were prepared separately and then mixed in 1 : 1 molar ratio.
Li, "Solvent-induced structural transition of self-assembled dipeptide: from organogels to microcrystals," Chemistry--A European Journal, vol.
A part of dipeptide derivatives (5a-c) form six-membered ring compounds (2,5-diketopiperazine: DKP (11) [27]), which may not polymerize anymore.
A prediction method named CryoProtect that is based on a random forest classifier and the combination of amino acid composition and dipeptide composition is proposed herein.
These five major constituents are the cyclic lipopeptide Gramicidin S (Rt: 9.08 min) and four cyclic dipeptides (CDPs) identified as cyclo(L-4-OH-Pro-L-Leu) (Rt: 4.08 min), cyclo(L-Tyr-L-Pro) (Rt: 4.83 min), cyclo(LPhe-L-Pro) (Rt: 5.18 min), and cyclo(L-Leu-L-Pro) (Rt: 5.87 min).
The oldest findings already show that supplementation of [beta]-alanine causes the increase of muscle carnosine dipeptide stocks ([beta]-alanyl-L-histidine) by 50%, which is an intramuscular pH buffering that has proven quite effective in exercise.
The 24 papers in this collection explore the chemistry, function, and laboratory analysis of imidazole dipeptides as nutritional components.
Dupin, "Biological role of histidine dipeptides in excitable tissues," Voprosy Medicinskoj Chimii, vol.