If the DRG is injured, it causes corresponding injury to the dorsal columns
and renders them unusable to modulation by SCS;  any modulation target is then selected 'deeper' to this level, e.
Although cerebellar damage also has to be considered, it is more likely that this patient's balance issues are connected with nerve damage to her dorsal columns
resulting in a loss of proprioception in her feet.
Severe attenuation or abolishment of all SEPs occurs in primates when the dorsal columns
of the upper thoracic, or mid cervical aspects of the spinal cord are ablated.
Damage to the dorsal columns
results in ipsilateral loss of proprioception and fine touch below the level of the lesion.
Sparing of the dorsal columns
was evident from preservation of deep touch, proprioception and vibration sense in all limbs.
12] deficiency are 1) Hematologic: megaloblastic anemia and pancytopenia (leucopenia, thrombocytopenia); 2) Neurologic: paresthesias, peripheral neuropathy, and combined systems disease (demyelination of dorsal columns
and corticospinal tract); 3) Psychiatric: irritability; personality change; mild memory impairment, dementia; depression; and psychosis; and 4) Cardiovascular: possible increased risk of myocardial infarction and stroke.