dosage compensation

(redirected from Dosage compensation effect)
Also found in: Medical.

dosage compensation

[′dō·sij ‚käm·pən‚sā·shən]
(genetics)
A mechanism that equalizes the expression in males and females of genes located on the X chromosome, despite their presence in two doses in the homogametic sex and a single dose in the heterogametic sex.
A mechanism that equalizes the expression of X-linked and autosomal genes by doubling the expression level of X-linked genes in male Drosophila and in both male and female mammals with their single active X.