epidermolysis bullosa

(redirected from Dystrophic Epidermolysis Bullosa)
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epidermolysis bullosa

[‚ep·ə·dər′mäl·ə·səs bu̇′lō·sə]
(medicine)
A congenital skin disease characterized by the development of vesicles and bullae upon slight, or even without, trauma.
References in periodicals archive ?
Biotechnology company Phoenix Tissue Repair Inc revealed on Tuesday that it has received US Food and Drug Administration (FDA) fast track designation to facilitate the development and expedite the review of PTR-01 for the treatment of recessive dystrophic epidermolysis bullosa (RDEB), a rare genetic disorder associated with severe skin blistering and treatment is currently limited to palliative options.
THE FOOD AND DRUG ADMINISTRATION has granted breakthrough therapy status to Abeona Therapeutics's EB-101 gene therapy program for patients with recessive dystrophic epidermolysis bullosa, according to a company statement.
"In June, we expect to report primary endpoint results from our Phase II clinical trial of azficel-T for the treatment of vocal cord scarring and also initiate a Phase I clinical trial of FCX-007, our orphan gene-therapy product candidate for the treatment of recessive dystrophic epidermolysis bullosa."
Sohana suffers from recessive dystrophic epidermolysis bullosa, which makes her skin so fragile her parents are barely able to cuddle her.
The diseases include phenylketonuria, sickle cell anemia, dystrophic epidermolysis bullosa, X-linked hypohidrotic ectodermal dysplasia, and Friedreich's ataxia-just a few of the more than 1000 genetic disorders that are well-described and many more that are not.
The money will go to Prostate Cancer UK Carney's Community, which works with disadvantaged young people, and the Sohana Research Fund, set up to support Sohana Collins, 13, who suffers from Recessive Dystrophic Epidermolysis Bullosa, or RDEB.Known as the Butterfly Disease, this is an incurable and often fatal illness which causes the skin to badly blister.
When the most viable, modified stem cells were selected, transplantation onto immunodeficient mice regenerated skin that did not blister in the mouse model system for recessive dystrophic epidermolysis bullosa and produced functional type VII collagen.
When the most viable, modified stem cells were selected, transplantation onto immuno-deficient mice regenerated skin that did not blister in the mouse model system for recessive dystrophic epidermolysis bullosa and produced functional type VII collagen.
Sohana suffers from a rare, life-threatening skin condition - recessive dystrophic epidermolysis bullosa (RDEB) - which affects around 8,000 children and adults in the UK.
INTRODUCTION: Dominant dystrophic Epidermolysis Bullosa (EB) is a subtype of dystrophic type of Epidermolysis Bullosa.
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