ED50


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Related to ED50: therapeutic index, TD50

ED50

(pharmacology)
References in periodicals archive ?
Amlodipine co-administered with gabapentin enhanced, in a dose-dependent manner, the anti-electro shock action of gabapentin by significantly reducing its ED50 value on the maximal electroshock induced seizures.
ED50 and ED95 of intrathecal hyperbaric bupivacaine coad-ministered with opioids for cesarean delivery.
La intencion del datum ED50 (European Datum 1950) fue dotar a toda Europa de una homogeneidad geodesica que los sistemas locales no poseian, siendo este en Espana oficial hoy en dia.
Muzi's dosages were selected because of a previous study by Ben-Shlomo et al (12) (1990) showing that Fentanyl and Midazolam act synergistically and that 25% of the ED50 of Fentanyl was required in combination with 23% of the ED50 for Midazolam to achieve the ED50 of the combination.
This is the first study that calculates ED50 and ED95 of spinal anesthesia for use in morbidly obese patients in cesarean delivery.
Therefore the estimated ratios of ED50 were calculated and the null hypothesis that the indices are equal to 1 was tested.
ED50 of hyperbaric bupivacaine with fentanyl for cesarean delivery under combined spinal epidural in normotensive and preeclamptic patients.
Guaifenesin protected the studied animals against PTZ-induced death with an ED50 of 328 mg/kg (table 1).
Successful anaesthesia or tourniquet pain block were taken as endpoints for calculating the ED50 of spinal bupivacaine.
Based on the ED50 of oridonin [23], high levels oridonin in rats observed in the present study is helpful to exert its anticancer activity in vivo.
In the case of a GalNAc-conjugated siRNA targeting transthyretin (TTR), target gene silencing was achieved with an ED50 of approximately 5 mg/kg with a single subcutaneous injection.