ED50


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ED50

(pharmacology)
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
antagonist developed by us); 4) DOX at ED50 5) 5-FU at ED50; 5) 2.5nM
The effect of the aqueous extract on delaying myoclonic (slope, 0.052 [+ or -] 0.006; P < 0.001), clonic (slope, 0.062 [+ or -] 0.008; P < 0.001), and tonic (slope, 0.219 [+ or -] 0.028; P < 0.001) seizures was dosedependent with an ED50 of 1257, 929, and 2142 mg/kg, respectively.
Ma: Coin, Arroyo del Corcho, 30SUF3953 (ED50), 450 m, aluvial (gneises y peridotitas), borde de arroyo, sauceda, 23-IV-2012,
The values of ED50 further showed that elevated CO2 caused a 11% increase in glyphosate tolerance in S biotype, but reduced the resistant level in R biotype by 60% (Table 1).
The combined ED50 all of microsecond exposures was 495 mJ/[cm.sup.2] and 386 mJ/[cm.sup.2] for the 1-hour and 24-hour observation points (n = 80), respectively.
falciparum in infected whole cells (erythrocytes) with ED50 values down to 55 nM.
The ED50 for this effect was determined to be 0.0015-0.0023 ng/mL as compared to 0.0021-0.0035 ng/mL for the competitor's mouse GM-CSF protein.
However, the protective effect obtained with DDM-GSH (ED50 = 0.68 mmol/kg ip) was 2.2-fold higher (P < 0.01) than that shown with NAC ([ED.sub.50] = 1.49 mmol/kg ip) (Figure 4).
The ED50 values (the concentration that produces 50% reduction of parasitemia) of the drug alone and in combination were calculated by plotting the log dose versus relative percentage inhibition using GraphPad Prism 4 Software (GraphPad Prism 4, CA, USA) using nonlinear regression, dose-response curve according to the 4-parameter logistic equation (Hill slope).