ED50


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Related to ED50: therapeutic index, TD50

ED50

(pharmacology)
References in periodicals archive ?
Using SPSS software, probit regression analysis was performed to obtain the ED50 and ED90 values of bupivacaine for the success of anaesthesia or block of tourniquet pain.
Furthermore, this global difference can be explained in large part by a combination of differences in ED50 and maximal response of the curves (F = 5.
Pre-clinical data from the ALN-PCS program have shown specific silencing of PCSK9 messenger RNA (mRNA) in the liver, and plasma PCSK9 protein levels of up to 90%, with an ED50 (the dose that provides a 50% silencing effect) of approximately 0.
These data demonstrate dose-dependent silencing of protein C mRNA with silencing of greater than 90% and an ED50 of approximately 0.