The increased EpCAM
protein expression was demonstrated in patients with a histological type of adenocarcinoma without a mucinous component than in those with adenocarcinoma with a mucinous component (p=0.028) (Table 1).
The diagrams show the concentrations of missed EVs ([mAb.sup.+][marker.sup.-]), detected EVs ([mAb.sup.+][marker.sup.+]), and possibly falsely detected EVs ([mAb.sup.-][marker.sub.+).] The sensitivity to detect EpCAM
particles was calculated from Fig.
Chang et al., "Lynch-like syndrome: characterization and comparison with EPCAM
deletion carriers," International Journal of Cancer, vol.
Recent research conducted by Sook & Keun (2014) to compare protein expression between intraoral BCC and peripheral ameloblastoma detected with 50 different types of antisera also showed that intraoral BCC showed strong positive results against EpCAM
 (Figure 5).
For the expression of EpCAM
, the internal control was the positive labeling oft his protein in the bile duct epithelium.
This intergenic SNP is located between the BCYRN1 and EPCAM
genes on Chromosome 2, and a functional link to BCYRN1 has been annotated for the region (http://www.varsome.com, http://www.noncode.org).
Faqih, "Tufting enteropathy and chronic arthritis: a newly recognized association with a novel EpCAM
gene mutation," Journal of Pediatric Gastroenterology and Nutrition, vol.
Schmidt et al., "The cell-cell adhesion molecule EpCAM
interacts directly with the tight junction protein claudin-7," Experimental Cell Research, vol.
Additionally, the protein EPCAM
, which is expressed in undifferentiated embryonic stem cells (ESCs), is associated with malignant nonseminomatous GCTs and has been suggested as a serum diagnostic marker in the treatment of GCTs [26, 27].
The specific high-risk genes are BRCA1, BRCA2, RAD51C, RAD51D, and BRIP1, plus Lynch syndrome (MLH1, MSH2, MSH6, PMS1, and EpCAM
), and the minimum surgery for these women is a risk-reducing salpingo-oophorectomy (RRSO).
Only four of the Food and Drug Administration (FDA)-approved markers (CA 15-3, CA 27.29, HER- 2/neu, and circulating tumor cells analysis of EpCAM
, CD45, CK8, 18, 19) can be measured and assessed longitudinally.
Cells were also stained with APC (allophycocyanin)-conjugated rat anti-mouse EpCAM