NGL

(redirected from ERBB2)
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Related to ERBB2: ERBB3, HER2, EGFR

NGL

A dialect of IGL.
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References in periodicals archive ?
(47) These markers included GATA3, CK18, CK20, uroplakin II, cyclin D1, and ERBB2 for the luminal markers; CK5/6, CK14, and p63 for the basal markers; and p16, B-cell lymphoma 2 (BCL2), smooth muscle actin (SMA), myosin, calponin, and desmin for the p53-like subtype markers.
One set of experiments involved using a virus to target ERBB2 receptors.
The HER family of tyrosine kinase receptors consists of EGFR, HER2 (ErbB2), HER3, and HER4.
The predictive model was calculated as the sum of the predictor values weighted by regression coefficients and included the addition of cetuximab to chemotherapy ([beta]=+1.771), mutations in 6 genes: ATP6V1B1 ([beta]=-0.165) CUL9 ([beta]=-0.726), ERBB2 ([beta]=-1.140), LY6G6D ([beta]=-0.994), PTCH1 ([beta]=+0.821), and RBMXL3 ([beta]=-0.477), and constant value (a=-0.255).
Denny et al., "Specific, irreversible inactivation of the epidermal growth factor receptor and erbB2, by a new class of tyrosine kinase inhibitor," Proceedings of the National Academy of Sciences of the United States of America, vol.
A retrospective analysis of the NSABP B-31 study indicated that ERBB2 and ESR1 mRNA levels influence the degree of benefit that is received from adjuvant trastuzumab [99].
The estrogen (ER) and the progesterone (PR) receptor status were determined by immunohistochemistry, the expression of ERBB2 with the HercepTest[R] (Dako) by use of FISH analysis for cases with 2 + staining as described elsewhere (8).
Based on our review of the literature and data on EGFR -targeted resistance to lung cancer, as well as on previous findings from our institution, seven target oncogenes ( EGFR , KRAS , PIK3CA , BRAF , ERBB2 , NRAS , and BIM ) that are closely related to the targeted therapy resistance of the EGFR gene were used in the polygenic primer panel.
The inhibition of HSP90 by 17-AAG depletes ErbB2, EGFR, phosphorylated AKT, and other oncogenic proteins involved in tumor progression.
Out of 160 proteins that passed quality control, six were associated with the MetS score: three (TNFSF14, HGF, and FGF-21) with MetS score and BMI, two (SCF and ERBB2) with MetS score and triglyceride levels, and one (Furin) with MetS score, BMI, and triglyceride levels.