EDTA

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EDTA:

see chelating agentschelating agents
. Certain organic compounds are capable of forming coordinate bonds (see chemical bond) with metals through two or more atoms of the organic compound; such organic compounds are called chelating agents.
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EDTA

(organic chemistry)
References in periodicals archive ?
Edetate calcium disodium forms stable chelates with a number of metals, but it is primarily used for lead overdose, either alone or in combination with dimercaprol.
Edetate calcium disodium (lead) is used either alone or in combination with dimercaprol.
The only effective test used for bone lead levels is the disodium edetate (EDTA) chelating agent test.
When routine screening tests performed after the gunshot wound revealed an elevated lead level, the patient was admitted to the hospital for chelation therapy with edetate calcium disodium (CaEDTA).
Each vial of EMEND for Injection for intravenous administration contains 188 mg of fosaprepitant dimeglumine equivalent to 115 mg of fosaprepitant and the following inactive ingredients: edetate disodium (14.
An additive often used in these preparations is disodium edetate (EDTA).
Tenders are invited for Procurement of (a) niv/pul/0049 inj ceftriaxone 2000 mg+ disodium edetate 74 mg+sulbactum 1000 mg, (b niv/pul/0050 inj ceftriaxone 1000 mg+ sulbactum 500 mg+ disodium edetate 37 mg.
8,17) Based on the package insert information, the brand name product was reformulated in 2005 from containing no excipients or preservatives to containing edetate disodium dehydrate and sodium citrate.
Disodium edetate (Reidel Dehan AG sleeze Hannover) sodium chloride NaCl (Merck) sodium hydroxide (Fluka AG) chloroform (Merck) DTNB of Sigma company cadmium acetate (Sigma) Reduced form of GSH of Fluka HCl 35% (Kolchlight) distilled water double refined potassium dihydrogen phosphate (Merck) water for injection (Elexor laboratories).
5 mg/kg IM); calcium glubionate (100 mg/kg PO); calcium gluconate (100 mg/kg IM); supplemental fluids (45 mL/kg SC; Normosol-R, Hospira, Inc, Lake Forest, IL, USA); doxycycline (60 mg/kg IM; Vibravenos formulation, Pfizer Laboratories, London, Ontario, Canada); vitamins A, D, and E (3300 IU/kg IM; Northwest Pharmacy and Compounding Center, Houston, TX, USA); and edetate calcium disodium (35 mg/kg IM; calcium disodium versenate, 3M Pharmaceuticals, Northridge, CA, USA).
In this current clinical study, the doctors compared different chelation protocols and two forms of EDTA (sodium calcium edetate and sodium edetate) in treatments of toxic metal exposure.
It has been shown that recovery of serum calcium concentrations following an acute lowering with edetate calcium disodium (EDTA) is unaffected in patients taking pamidronate (a bisphosphonate similar to alendronate) chronically for osteoporosis (13).