Edman degradation technique

Edman degradation technique

[′ed·mən ‚deg·rə′dā·shən tek‚nēk]
(biochemistry)
In protein analysis, an approach to amino-end-group determination involving the use of a reagent, phenylisothiocyanate, that can be applied to the liberation of a derivative of the amino-terminal residue without hydrolysis of the remainder of the peptide chain.