Expression of aquaporins in the efferent ductules, sperm counts, and sperm motility in estrogen receptor-alpha deficient mice fed lab chow versus casein.
Aquaporin-1 and -9 are differentially regulated by oestrogen in the efferent ductule epithelium and initial segment of the epididymis.
The male reproductive system of Phrynops geoffroanus consists of a pair of testes, from which narrow efferent ductules
emerge to form the epididymis, which uncoil in the caudal portion and continue on to the deferent duct, all of which are involved by the urogenital mesentery.
The excurrent ducts are further divided into the efferent ductules
(EDs), epididymis, and vas deferens (Figure 3).
22,23) These elegant studies have demonstrated the presence of precursor lesions confined to the efferent ductules
of the head of the epididymis.
However, various reports are found on the epididymal presence of aromatase in human efferent ductules
and proximal epididymis (Carpino et al.
These lesions are typically cystic dilatations of tubules of the efferent ductules
in the head of the epididymis.
ABSTRACT : Our earlier studies showed that estrogen was involved in the regulation of fluid reabsorption in adult mouse efferent ductules
(ED), through estrogen receptor (ER) [alpha] and ER[beta], by modulating gene expression of epithelial genes involved in ion homeostasis.
The mature spermatozoa then exit the seminiferous tubules, enter the rete testis and efferent ductules
, and move into the epididymis, where they are rendered motile and fertile and are stored.