electrophilic

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electrophilic

[i¦lek·trō′fil·ik]
(physical chemistry)
Pertaining to any chemical process in which electrons are acquired from or shared with other molecules or ions.
Referring to an electron-deficient species.
References in periodicals archive ?
Importance of phase 2 gene regulation in protection against electrophile and reactive oxygen toxicity and carcinogenesis.
After direct attack by electrophiles or ROS or indirect actions such as phosphorylation, Nrf2 is released from Keap1 repression, translocated into nucleus where it activates the transcription of a variety of detoxifying enzyme genes through the ARE45.
The different MAPEG members display distinct or overlapping physiological functions, including reduction of lipid hydroperoxides (glutathione peroxidase), detoxication of reactive electrophiles (glutathione transferase), and production of leukotrienes and prostaglandin E (Schmidt-Krey et al.
As a result of the conjugation reaction between electrophiles and GSH, a conjugate that is generally less reactive than the parental compound is formed and the solubility of hydrophobic xenobiotics is increased.
They explain how to differentiate between electrophiles and superelectrophiles, discuss ways to increase electrophilic strength, and review the role of electrophilic salvation in chemical reactions as studied by kinetic investigations, spectroscopic studies, gas-phase studies, and theoretical methodologies.
Carboranes: a new class of weakly coordinating anions for strong electrophiles, oxidants, and superacids.
gamma]-Tocopherol traps mutagenic electrophiles such as NO(X) and complements [alpha]-tocopherol: physiological implications.
Interesting, traditional electrophiles such as imines, ketones or aldehydes have remained unreactive under Pd-catalyzed coupling conditions.
Fluorinated radicals behave as electrophiles and their addition is retarded by electron withdrawing and accelerated by clectron donating substituents on the olefin.
A Simple Diversity Linker Strategy Using Immobilised Enol Phosphonates as Electrophiles for Suzuki-Miyaura Reactions
a) Sulforaphane up-regulate genes that influence an aerobic cell's ability to protect against oxidative stress, inflammation, DNA-damaging electrophiles, and radiation