electroporation

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electroporation

[i‚lek·trō·pə′rā·shən]
(biology)
The application of electric pulses to increase the permeability of cell membranes.
(cell and molecular biology)
The application of electric pulses to animal cells or plant protoplasts to increase membrane permeability.
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With the exception of the cost for an electroporator machine, the electroporation method is advantageous because of large scale transfection and no need for a transfection reagent.
VGX's clinical development programs include PENNVAX[TM]-B, a DNA vaccine for the prevention of HIV in Phase I clinical trials; VGX-1027, a small molecule drug for inflammatory diseases in Phase I clinical trials; VGX-3100, a DNA therapeutic vaccine for cervical cancer in Phase I clinical trials; and the CELLECTRA[R] electroporator, a DNA delivery device in Phase I clinical trials.
However, implementation of the compensation circuit without preliminary analysis of the transient processes could result in an over-damped or under-damped response, which is in both cases undesirable and may result in irreversible damage of the electroporator or poor pulse generation flexibility.
Jurkat cells were resuspended in 350[micro]1 and transfected by electroporation using an Easyject plus Electroporator (Equibio, Middlesex, UK).
The Company has been developing the CELLECTRA[TM] electroporator as its lead clinical medical device for delivering DNA vaccine and therapy products.
Tenders are invited for Supply and installation of electroporator
VGX's research pipeline includes a new generation of DNA vaccines and therapeutics as well as CELLECTRA[TM] electroporator, a patented DNA delivery device.
Versatile and modular electroporator for reproducible transformation of prokaryotic acterial, yeast & microorganisms) and eukaryotic cells (insects)
Limited Tenders are invited for Purchase Of Cell Electroporator Total System
Contract awarded for Supply, Delivery, Installation And Commissioning Of Multimode Plate Reader (1 Unit), Electroporator (1 Unit), Analytical Balance (6 Units) and Precision Balance (6 Units) For Lee Kong Chian School Of Medicine
Tenders are invited for Purchase of electroporator - 02 nos