The scientists believe that they have developed a method, called Paired Ion Electrospray Ionisation
(PIESI) that builds on existing mass spectrometry techniques to detect these extremely small metabolites and uses a chemical agent to bind to the minute pieces of steroid or amphetamine and make them more visible to the detector.
The kit is to be used for electrospray ionisation
liquid chromatography-mass spectrometry.
The compounds in their breath were analysed by means of a technique called secondary electrospray ionisation
mass spectrometry (SESI-MS), which is capable of detecting extremely small elements of the chemicals present in their breath.
Haemoglobin Sodertalje (beta118 Phe-_Val): a new mutation in human haemoglobin identified by electrospray ionisation
The ability to analyse polar, nonvolatile biological molecules was realised with the introduction of "soft" ionisation techniques such as fast atombombardment (FAB/MS), thermospray (TSI/MS), and most recently and importantly, electrospray ionisation
(ESI/MS) which allows liquid chromatography to interface with mass spectrometry.
Study of the mass spectrometric behaviour of phthalocyanine and azo dyes using electrospray ionisation
and matrix-assisted laser desorption/ionisation, Rapid Communications in Mass Spectrometry (2001) 15:2076-2084.
analysis of human fibrinogen.