The PLLA and PDLA
enantiomer generate polar interactions with sc-DME to dissolve efficiently because DME has a dipole moment of 1.3 D [18].
Pyrethroid Achiral (Diastereomers) and Chiral (
Enantiomers) Analysis
The novel polyphosphoester P-12 and some anthracene-derived compounds, among them, the a-aminophosphonates A-3-A-6, their precursors the Schiff bases S-1 and S-2, the bis-aminophosphonate B-6, the two
enantiomers A-5a and A-5b of the racemic A-5, and the polyphosphoesters P-8-P-11, containing aminophosphonate units, have been tested for cytotoxicity against a panel of human tumor cell lines: HL60, SKW-3, REH, and K-562.
The method validation was performed on spiked biological samples and found to produce complete separation of the synthetic cathinone
enantiomers on achiral capillary GC column in addition to sensitive detection of low concentrations in the [micro]g/L range better than the previous reported methods that use EI and positive CI ionization mass spectrometry.
In these latter two cases, the effect of separating the racemic mixture into
enantiomers is "unexpected" in the sense that we could not have known in advance that there would be such a multiplier effect in this particular case.
(2009) Chiral polymers for resolution of
enantiomers. J.
In this research, a novel method was presented based on the resonance of light scattering for the measurement of
enantiomers of the target components in the presence of one another.
The optical resolution of racemates has been essential in the perfume production pharmaceutical industry food preparation and so forth due to the harmful effect of one of the
enantiomer of racemate mixture.
The two linalool
enantiomers were identified by both retention time and corresponding mass spectra (results not shown).
Only one chiral stationary phase was reported in literature for efficient separation of HBCD
enantiomers. Baseline resolution of the 6
enantiomers from an [alpha]-, [beta]-, and [gamma]-HBCD mixture was achieved on [beta]-permethylated cyclodextrin bonded (NUCLEODEX, Macherey-Nagel, GmbH, Diiren, Germany) chiral LC column (4 x 200 mm, 5[micro]m) [96].
Pharmacokinetic differences between the
enantiomers could be caused by chiral inversion.
Different pharmacological properties of two
enantiomers in a unique beta-blocker, nebivolol.