The PLLA and PDLA enantiomer
generate polar interactions with sc-DME to dissolve efficiently because DME has a dipole moment of 1.3 D .
Pyrethroid Achiral (Diastereomers) and Chiral (Enantiomers
The novel polyphosphoester P-12 and some anthracene-derived compounds, among them, the a-aminophosphonates A-3-A-6, their precursors the Schiff bases S-1 and S-2, the bis-aminophosphonate B-6, the two enantiomers
A-5a and A-5b of the racemic A-5, and the polyphosphoesters P-8-P-11, containing aminophosphonate units, have been tested for cytotoxicity against a panel of human tumor cell lines: HL60, SKW-3, REH, and K-562.
The method validation was performed on spiked biological samples and found to produce complete separation of the synthetic cathinone enantiomers
on achiral capillary GC column in addition to sensitive detection of low concentrations in the [micro]g/L range better than the previous reported methods that use EI and positive CI ionization mass spectrometry.
In these latter two cases, the effect of separating the racemic mixture into enantiomers
is "unexpected" in the sense that we could not have known in advance that there would be such a multiplier effect in this particular case.
(2009) Chiral polymers for resolution of enantiomers
In this research, a novel method was presented based on the resonance of light scattering for the measurement of enantiomers
of the target components in the presence of one another.
The optical resolution of racemates has been essential in the perfume production pharmaceutical industry food preparation and so forth due to the harmful effect of one of the enantiomer
of racemate mixture.
Only one chiral stationary phase was reported in literature for efficient separation of HBCD enantiomers
. Baseline resolution of the 6 enantiomers
from an [alpha]-, [beta]-, and [gamma]-HBCD mixture was achieved on [beta]-permethylated cyclodextrin bonded (NUCLEODEX, Macherey-Nagel, GmbH, Diiren, Germany) chiral LC column (4 x 200 mm, 5[micro]m) .
Pharmacokinetic differences between the enantiomers
could be caused by chiral inversion.
Different pharmacological properties of two enantiomers
in a unique beta-blocker, nebivolol.