Splenomegaly

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splenomegaly

[‚splē·nə′meg·ə·lē]
(medicine)
Enlargement of the spleen.

Splenomegaly

 

in medicine, the enlargement of the spleen. Splenomegaly occurs with diseases of the spleen (tumors, cysts, abscesses), with general infections (sepsis, malaria, typhoid fever, typhus), with blood diseases (leukoses, lymphgranulomatos-es), and with liver diseases. The spleen is examined by palpation while the individual is lying on his side; it will not be felt if its size is normal.

Splenomegaly is often the first manifestation of blood disease. In such cases, splenic puncture is performed in order to make an accurate diagnosis. With chronic leukoses, the spleen may occupy most of the abdomen and weigh as much as 8 kg. Splenomegaly is accompanied by disruption of breathing, blood circulation, and the functions of adjacent organs, including the stomach, intestine, and left kidney. Disturbances of splenic blood circulation (thromboses), suppression of hematopoiesis (hypersplenism), and other complications may also occur. The condition is treated by surgically removing the spleen (splenectomy), by irradiating the spleen with gamma rays, and by administering cytostatics and corticosteroids.

References in periodicals archive ?
3 center Byers did not participate in the scrimmage because he is recovering from an enlarged spleen.
McMullen, who was serving a sentence for a probation violation on a drunken driving charge at the time, suffered from advanced cirrhosis of the liver and an enlarged spleen, according to testimony at Mr.
The symptoms of acute infection--fever, weakness, enlarged spleen and lymph nodes, edema of the face and legs, and tachycardia--can last up to four months.
During a physical exam in 2001 an internist found that I had an enlarged spleen.
Smith, who played with an enlarged spleen because of a virus, scored 51.
Thrombocytopenia can occur due to decreased marrow production of megakaryocytes as in marrow infiltration with tumour, fibrosis or due to marrow failure in aplastic anaemia; splenic sequestration of circulating platelets in enlarged spleen in portal hypertension, etc.
Ultrasound scan revealed a normal liver, but an 8 cm diameter abscess within an enlarged spleen.
An enlarged spleen is found in 50% to 80% of malaria patients (1), while only 25 cases of splenic rupture have been reported since 1960 (0%-2% in natural occurring infection) (5).
Pathology revealed an enlarged spleen measuring 15.
It has a historical use for enlarged spleen (a mass of lymphatic tissue), prostate conditions, and cough.
THE OTHER FORM IS INTERNAL, CAUSING FEVER, WEAKNESS, LOSS OF BODY WEIGH, AN ENLARGED SPLEEN AND A LOWERED BLOOD COUNT.
She was admitted to Wordsley Hospital in Stourbridge where a body scan revealed she had an enlarged spleen and heart valves as well as a heart murmur.