Entner-Doudoroff pathway


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Entner-Doudoroff pathway

[¦ent·nər ¦dō·də‚rȯf ‚path‚wā]
(biochemistry)
A sequence of reactions for glucose degradation, with the liberation of energy; the distinguishing feature is the formation of 2-keto-3-deoxy-6-phosphogluconate from 6-phosphogluconate and the cleaving of this compound to yield pyruvate and glyceraldehyde-3-phosphate.
References in periodicals archive ?
An analysis of the genome of SDSE 167 strain has shown that it excretes lyases decomposing carbohydrates of the host, while at the same time this genome metabolizes carbohydrates in the Entner-Doudoroff pathway; this region contains the enzyme metabolizing polysaccharides, which may contribute to a higher virulence of SDSE 167 strain [14].
Failure of [edd.sup.-] mutant of P putida in Entner-Doudoroff pathway was also shown, while this mutant strain was able to grow on D-fructose [46].
Prebiotic origin of glycolytic metabolism: histidine and cysteine can produce acetyl CoA from glucose via reactions homologous to non-phosphorylated Entner-Doudoroff pathway. J.