Enzyme Inhibitor


Also found in: Dictionary, Medical, Wikipedia.

Enzyme Inhibitor

 

a chemical substance that selectively inhibits the activity of an enzyme or a group of related enzymes. Even in very low concentrations, enzyme inhibitors repress an organism’s vital physiological functions. Many toxic substances, including pesticides, such nerve gases as lewisite, and such respiratory toxins as cyanides and hydrogen sulfide, have a toxic effect owing to the inhibition of enzymes, for example, the enzyme cholinesterase in arthropods.

The study of the effect of enzyme inhibitors on enzymes or groups of enzymes facilitates the search for antidotes or for new pesticides to control harmful insects, mites and ticks, and weeds. The term “enzyme inhibitors” sometimes refers to enzymes in the poisons of snakes, bees, and scorpions that destroy tissues or blood cells in man and animals.

References in periodicals archive ?
One group received calcium channel blockers (CCBs), and the other group received angiotensin converting enzyme inhibitors (ACEIs) daily for duration of 6 months from the day of enrolment during the one year study period.
Effect of the angiotensin-converting enzyme inhibitor benazepril on the progression of chronic renal insufficiency.
Entacapone, a COMT enzyme inhibitor used in the treatment of Parkinson's disease, is Orion Pharma's patented molecule discovery, available globally as Comtess and Comtan.
Juan Leon, from the same laboratory (NWU), showed that captopril, an antifibrotic angiotensin-converting enzyme inhibitor, is effective in ameliorating experimental autoimmune myocarditis and experimental Chagas heart disease.
The cyclooxygenase-2 (COX-2) enzyme inhibitor celecoxib in combination with risperidone improved both positive and negative symptoms of schizophrenia more than treatment with risperidone alone, said Dr.
Angiotensin-converting enzyme inhibitor therapy ought to be extended to a vastly expanded patient population.
Similarly, some vendors are increasingly outsourcing part of their enzyme inhibitor drug manufacturing or the entire manufacturing process to various contract manufacturing organizations.
The tender number includes the following medicines: Tender no: 1, Atc code: J01cr05, Generic name: Piperacillin and enzyme inhibitor, Dispensing form: Pul.
The product is an oral beta-secretase 1 cleaving enzyme inhibitor.
The most up-to-date South African Hypertension Guideline states that the choice of therapy for either an angiotensin converting enzyme inhibitor (ACEI) or an angiotensin receptor blocker (ARB) should be based on cost and tolerability.
He was treated with aspirin, [beta] blocker, clopidogrel, low molecular weight heparin, angiotensin converting enzyme inhibitor and intavenous nitroglycerin.