Enzyme Inhibitor

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Enzyme Inhibitor

 

a chemical substance that selectively inhibits the activity of an enzyme or a group of related enzymes. Even in very low concentrations, enzyme inhibitors repress an organism’s vital physiological functions. Many toxic substances, including pesticides, such nerve gases as lewisite, and such respiratory toxins as cyanides and hydrogen sulfide, have a toxic effect owing to the inhibition of enzymes, for example, the enzyme cholinesterase in arthropods.

The study of the effect of enzyme inhibitors on enzymes or groups of enzymes facilitates the search for antidotes or for new pesticides to control harmful insects, mites and ticks, and weeds. The term “enzyme inhibitors” sometimes refers to enzymes in the poisons of snakes, bees, and scorpions that destroy tissues or blood cells in man and animals.

References in periodicals archive ?
Angioedema incidence in US veterans initiating angiotensin-converting enzyme inhibitors.
The classifications, comparisons and usage of enzyme inhibitors are also portrayed in this report.
Good evidence exists to support the use of key secondary prevention medications (a four-drug combination of aspirin, statins, beta-blockers and angiotensin-converting enzyme inhibitors or angiotensin receptor blockers) and smoking cessation in patients after acute coronary syndromes (ACSs).
Evaluation of enzyme inhibitors in drug discovery; a guide for medicinal chemists and pharmacologists, 2d ed.
Page 245-250/Sayfa 245-250: The effects of chronic usage of enzyme inhibitors and angiotensin receptor blockers on contrast-induced nephropathy in low-risk patients Nezihi Baris, Ebru Ozpelit, Nazile Bilgin Dogan, Hande Kangul, Sefa Gul, Bahri Akeniz, Sema Guneri
Our vision is to provide fundamental structural and mechanistic-dissection of key proteins and their complexes and to use these as the foundation to deliver enzyme inhibitors as tools to probe the cellular function of specific glycans.
A new study finds that giving enzyme inhibitors to rats in shock can alleviate the potentially lethal condition.
Researchers sought to determine whether enzyme inhibitors could reduce shock rates.
The other two volumes in the series treat enzyme technologies in drug discovery, and the design of enzyme inhibitors for therapeutics.
An evaluation of risk factors for adverse drug events associated with angiotensin-converting enzyme inhibitors.
LOS ANGELES -- The use of angiotensin-converting enzyme inhibitors is associated with a significantly lower risk of developing esophageal, pancreatic, and colon cancers, according to research presented at the annual Digestive Disease Week.
Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists.