Esophagitis

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Related to Eosinophilic esophagitis: Eosinophilic gastroenteritis

esophagitis

[ə‚säf·ə′jīd·əs]
(medicine)
Inflammation of the esophagus.

Esophagitis

 

inflammation of the mucosa of the esophagus. Esophagitis may be an independent disease or, more often, a symptom of another disease of the esophagus, stomach, or other organ. The inflammation is frequently caused by chemical, mechanical, or thermal irritation of the esophagus; for example, it may be caused by eating very hot and spicy food.

Catarrhal, phlegmonous, necrotic, and other forms of esophagitis are distinguished based on the severity of the inflammatory changes. In severe cases the inflammatory process may extend to the muscular layer of the esophagus, and sometimes, to the surrounding mediastinal tissue, giving rise to mediastinitis. One form of the disease, peptic esophagitis, is caused mostly by a reflux of the acidic contents of the stomach into the esophageal lumen in cases of hiatus hernia. Peptic esophagitis is sometimes associated with the development of an ulcer in the esophageal wall.

The course of the disease may be acute or chronic. Chronic esophagitis is frequently caused by alcohol abuse or smoking. The symptoms include a burning sensation, retrosternal pain on swallowing, excessive salivation, and regurgitation of food. Esophagoscopy is sometimes used to diagnose the disease. Treatment is by diet (eliminating coarse, hot, and acidic foods), pain relievers, astringent and antispasmodic drugs, and, in some forms, antibiotics and surgery.

REFERENCE

Vasilenko, V. Kh., A. L. Grebnev, and M. M. Sal’man. Bolezni pishchevoda. Moscow, 1971.

I. V. IAREMA

References in periodicals archive ?
Eosinophilic esophagitis. N Engl J Med 2004; 351(9):940-941.
Eosinophilic esophagitis is predominantly seen in male patients between 30 and 40 years old.
Eosinophilic Esophagitis is a chronic, allergic inflammatory disease characterised by eosinophilic infiltration of the esophagus, which can lead to inflammation and ultimately strictures and narrowing of the esophagus, putting patients at risk of food impaction.
Mansoor explained that the data review suggested there may be some overlap in the genetic and environmental factors underlying eosinophilic esophagitis and celiac disease.
Collins, "Eosinophilic esophagitis in children and adults: a systematic review and consensus recommendations for diagnosis and treatment," Gastroenterology, vol.
Ishimaura et al., "Clinical characteristics of Japanese patients with eosinophilic esophagitis and eosinophilic gastroenteritis," Journal of Gastroenterology, vol.
Menard-Katcher, "Recognition and assessment of eosinophilic esophagitis: the development of new clinical outcome metrics," Gastroenterology and Hepatology, vol.
Although macroscopic esophageal candidal involvement was not reported in our case, biopsy evaluation as eosinophilic esophagitis and fibrosis might be a hint in that direction.
Spergel, "Eosinophilic esophagitis and gastroenteritis," Current Allergy and Asthma Reports, vol.
Gastroenterologists, nutritionists, and other clinicians from the US, Australia, and Canada discuss nutritional assessment; macronutrient digestion and absorption; malabsorption; food allergy and intolerance; prebiotics and dietary fiber; the role of intestinal microbiota and probiotics in health and disease; nutrition and gastrointestinal cancer, gastroesophageal reflux disease and eosinophilic esophagitis, celiac disease, irritable bowel syndrome, inflammatory bowel disease, and acute and chronic pancreatitis; enteral access and nutrition; parenteral nutrition; medical and endoscopic therapy and surgical management of obesity and complications; and nutritional counseling.
However, mixed type food allergies include both IgE-mediated and cell mediated mechanisms and clinical findings (eosinophilic esophagitis, eosinophilic gastritis, esosinophilic gastroenteritis) generally occur within a certain time after consumption of food (1, 2).
Eosinophilic esophagitis (EoE), once thought to be purely a pediatric disorder, is now recognized in adults as an allergic, possibly diet-induced reaction.

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