Aquaporin4 knockout mice develop marked hydrocephalus, probably because of reduced water clearance through the ependyma
and brain-blood barrier.
Guerra et al., "Astrocytes acquire morphological and functional characteristics of ependymal cells following disruption of ependyma
in hydrocephalus," Acta Neuropathologica, vol.
The structure of the cerebral ventricles is subjected to significant changes which enclose marked polymorphism of ependyma
cells, disturbances of their continuity of their layer at considerable length.
The CSF-lymphatic link into nasal submucosa effects the ependyma
and provides a regulatory mechanism which helps to balance the repetitive production and re-absorption of CSF (15).
Intermediate filament proteins in choroid plexus and ependyma
and their tumors.
Unfortunately, the ependyma
may be destroyed by significant dilatation of the central canal.
A few studies, however, indicated for an alternative pathway of virus entry following direct intbction of microvascular endothelial cells of the blood brain barrier (31), Following entry the second step is getting past the glia limitans (layer formed due to astrocytic end foot interdigitating with piamater along the surface and ependyma
along the ventricles) which is an additional barrier both functionally and structurally.
Medially the MD is lined with 3rd ventricular ependyma
lying immediately adjacent to the 3rd ventricle, except where the paraventricular nucleus is interposed.
Cell proliferation and nestin expression in the ependyma
of the adult rat spinal cord after injury.
Ependymomas originate from the ependyma
cells, which are lining the spinal cord's central canal.10 "These cells vary from cuboidal to flat and modulate the transfer of fluid between the cerebrospinal fluid (CSF) and the cells of the nervous system".
They were located near the soft cerebral membrane, chiefly in the regions of the posterior long fasciculi, the nuclei of the abducent vestibular and trigeminus nerves, under the ependyma
, in the area of the cochlear nerve nuclei, the Gover's fasciculi, and in the base of the cerebellum.