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Related to Ependymal cells: microglia, Satellite cells, Astrocytes, Oligodendrocytes, Blood brain barrier


The layer of epithelial cells lining the cavities of the brain and spinal cord. Also known as ependymal layer.



cells in the brain of animals and man that perform demarcating, supportive, and secretory functions in the central nervous system; a form of neuroglia.

The ependyma separates from cells of the neural tube in early embryogenesis. Ependymal cells (ependymocytes) line the walls of the spinal canal and ventricles of the brain. They have elongated bodies with cilia at the free end. The cilia, which are lost in many parts of the brain after the individual is born, help the cerebrospinal fluid to circulate by their beating movements. A long, branched process extends from the opposite end of the ependymocyte into the brain. The ependyma of the walls of the third ventricle may promote the exchange of biologically active substances between neurons of the adjacent regions of the brain, cerebrospinal fluid, and blood vessels of the hypophyseoportal system.

References in periodicals archive ?
Currently, when neural stem cells are harvested for growth in culture, however, the ependymal cells are not removed along with them.
Later it was found that not only embryonic CNS but also adult CNS possess the ability to generate neurospheres forming cells in vitro, including neural epithelial progenitor (NEP) cells, radial glial cells, SVZ cells, and ependymal cells, that clonigenically generate neurons, astrocytes and oligodendrocytes in vivo (16).
42,43) Apart from lymphatic endothelium, D2-40 has been reported to be immunoreactive in mesotheliomas (44,45) and, in the CNS, in choroid plexus epithelium, ependymal cells, subependymal areas, and the leptomeninges.
It is postulated that this tumor originates from the ependymal cells of lamina terminalis (1).
In all animals, a strong neuronal infection could be observed with viral antigen in the cytoplasm and nuclei of neurons, glial cells, and ependymal cells in the brain, spinal cord, and eye (Table 1, Figure 2, panels A, B).
Choroid plexus and ependymal cells are quite similar, with the latter showing more "degenerative" cytologic features and fewer cellular clusters.
Both spindle cells and ependymal cells were positive for vimentin.