epigenetics

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Related to Epigenetic regulation: Epigenetics, DNA methylation

epigenetics

[¦ep·ə·jə¦ned·iks]
(genetics)
The study of those processes by which genetic information ultimately results in distinctive physical and behavioral characteristics.
References in periodicals archive ?
Zhu, "Epigenetic regulation of stress responses in plants," Current Opinion in Plant Biology, vol.
Emerging evidence suggest that specific chromatin modifications, including the incorporation of distinct histone variants, covalent histone modifications, gene epigenetic regulation and chromatin remodeling are coordinately utilized in order to ensure the various plant hormone responses.
McEwen, "Stress and anxiety across the lifespan: structural plasticity and epigenetic regulation, " Epigenomics, vol.
The best described of these mechanisms is the methylation of DNA on cytosine bases, most often at CpG sites, that plays an important role in the epigenetic regulation of genomic imprinting, suppression of transposons and other parasitic sequences of DNA, and the inactivation of the X chromosome (Laurent et al., 2010).
(42) Methylation specifically occurs in exon 2, (43) and other promoter regions such as NFKappaB and SP1 show a similar epigenetic regulation (Fig.
Consistent with the concept of epigenetic regulation of gene expression, alterations in DNA methylation were associated with significant changes in the expression of 84 genes.
McGowan et al., Epigenetic Regulation of the Glucocorticoid Receptor in Human Brain Associates with Childhood Abuse, 12 NATURE NEUROSCIENCE 342 (2009).
Researchers from around the world working in the field and related disciplines discuss the roles of proteolysis in plant self- incompatibility, the epigenetic regulation of transposable elements in plants, proteins and interactions, expression quantitative trait loci analysis, plants' sensing and responding to excess light, phloem transport, cellulosic biofuels, jasmonate action, selaginella, the circadian system in higher plants, photorespiratory metabolism, environmental effects on the spatial and temporal patterns of leaf and root growth, genetically engineered plants and foods, and other topics.
The preliminary results indicate that global hypomethylation leads to a decrease in place field stability (p < 0.005) and suggest a potential role for epigenetic regulation in spatial learning and memory.
Of the >50 known modes of modification, including acetylation, methylation, phosphorylation, and ubiquitination, alterations in the histone tail exhibit the greatest range of variation in epigenetic regulation (1, 2).
"Epigenetic regulation in psychiatric disorders," Nature Reviews Neuroscience, May 2007.