Ergonovine


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Related to Ergonovine: ergonovine maleate
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Ergonovine

 

(also ergometrine), a uterine stimulant; one of the most common ergot alkaloids. Ergonovine is used in obstetrics in cases of uterine bleeding. It is administered orally in tablet form as well as by the intramuscular and intravenous methods.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
Ergonovine is an ergot derivative that causes uterine contractions and has been shown to effectively reduce blood loss at delivery.
The patient was diagnosed with TCM caused by previous CAG with ergonovine provocation test and was admitted for close observation.
Within the sacs are millions of tiny black spores containing several alkaloids, including ergonovine. Chemically known as lysergic acid, it is very similar structurally to a synthetic compound, d-lysergic acid diethylamide (LSD).
Menstrual migraine and intermittent ergonovine therapy.
Keywords: Dang-Qui-Shao-Yao-San; PG[F.sub.2]; Ach; Ergonovine; Propranolol; Oxytocin; KCl
The following DA antagonists were ineffective at [10.sup.-4] M: bulbocapine, butaclamol, ergonovine, apomorphine, chlorpromazine, fluphenazine, pimozide, spiperone, and sulpiride (Table 3).
High levels of ergonovine and lysergic acid amide in toxic Achnatherum inebrians accompany infection by an Acremonium-like endophytic fungus.
ergot: Spore-producing reproductive body of a fungus that infects grain crops; ergot contains lysergic acid and ergonovine.
In another case series report (N = 40), (33) ergonovine (0.2 mg 4 times daily, from day-1 to day +1 for 3 months) reduced the severity of attacks in 60% of participants, lessened the number of attacks in 15%, and had no effect in 35%.
Before the advent of triptans, ergot derivatives, including ergotamine tartrate, ergonovine, and dihydroergotamine, were utilized as the treatment of first choice for moderate to severe migraine when simple analgesics did not satisfactorily relieve migraine headache or when they produced significant side effects.[53] Ergot derivatives can be given perimenstrually as both acute and prophylactic treatment.[24] In a series of clinical trials ergotamine tartrate was proven to be effective in migraineurs.[67] It can be administered alone or in combination with caffeine.