ergotamine

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ergotamine

[ər′gäd·ə‚mēn]
(organic chemistry)
C33H35N5O5 An alkaloid found in the fungal parasite ergot; causes smooth muscles in peripheral blood vessels to constrict, limiting blood flow; used to treat migraine headaches.
References in periodicals archive ?
24,44] A double-blind study that compared the efficacy as well as safety of naproxen sodium and ergotamine tartrate in a sample of 79 participants with classical or common migraine found that naproxen sodium was as safe as ergotamine tartrate and somewhat more effective in acute migraine attacks.
ergotamine tartrate and caffeine tablets (marketed by West-Ward Pharmaceutical Corporation and Mikart), Cafergot tablets (marketed by Sandoz), and Ergo-mar sublingual tablets (marketed by Rosedale Therapeutics).
Because ergotamine tartrate and dihydroergotamine (DHE 45) can cause nausea and vomiting, they may be combined with anti-nausea drugs.
Ergotamine tartrate products are used to treat vascular headaches, including migraines.
Nausea and vomiting have been reported in up to 10% of persons receiving therapeutic doses of ergotamine tartrate.