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The current study represents a further contribution to the molecular characterization of B19V in Brazil since it presents an analysis of the genotypes circulating during two distinct outbreaks of erythema infectiosum in our country.
Cody was diagnosed with erythema infectiosum and was managed with symptomatic treatment.
In the present study, one B19 IgM positive patient developed features of erythema infectiosum in the form of atypical maculo-papular rashes on both the lower limbs which has seldom been reported (23,24).
In the early 1980s, it was demonstrated as an agent of human disease erythema infectiosum (fifth disease) in children, transient aplastic anemia and hydrops fetalis (3-7).
Erythema infectiosum fifth disease) is characterized by several days of high fever, migratory myalgias and arthralgias, lymphadenopathy, anemia, and the presence of a maculopapular rash that appears as the fever breaks.
The common name for erythema infectiosum came from its fifth position on a list developed in the early 1900s of childhood rash diseasaes.
The symptoms vary from a minor illness, possibly with headache, mild fever and sore throat, to erythema infectiosum, which produces a rash on the cheeks - hence its name 'slapped cheek'.