The current study represents a further contribution to the molecular characterization of B19V in Brazil since it presents an analysis of the genotypes circulating during two distinct outbreaks of erythema infectiosum
in our country.
Pregnant women are advised to avoid those with a known case of erythema infectiosum
because of the potential for complications, such as intrauterine death (Hay, Levin, Sondheimer, & Deterding, 2011).
In the present study, one B19 IgM positive patient developed features of erythema infectiosum
in the form of atypical maculo-papular rashes on both the lower limbs which has seldom been reported (23,24).
The most common clinical presentations of infection are fifth disease or erythema infectiosum
, arthropathy and hydrops fetalis, which are found among immunocompetent hosts (2), (3), (38).
[1.] Erythema infectiosum
fifth disease) is characterized by several days of high fever, migratory myalgias and arthralgias, lymphadenopathy, anemia, and the presence of a maculopapular rash that appears as the fever breaks.
The common name for erythema infectiosum
came from its fifth position on a list developed in the early 1900s of childhood rash diseasaes.
The symptoms vary from a minor illness, possibly with headache, mild fever and sore throat, to erythema infectiosum
, which produces a rash on the cheeks - hence its name 'slapped cheek'.
Parvovirus B19 causes erythema infectiosum
The common exanthems were numbered in the early 1900s and include in numerical order: rubeola, scarlet fever, Filatov-Dukes disease (now considered to be several viral diseases rather than a single entity), rubella, erythema infectiosum
(fifth disease), and roseola (sometimes called exanthem subitum or sixth disease) (Adams & Ware, 1996).