Erythroderma

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Erythroderma

the name for any of a group of diseases of humans manifested chiefly by an inflammatory reaction of the entire skin, including redness, edema, scaling, and itching. Primary erythrodermas occur as disease entities, for example, Ritter’s disease. Secondary erythrodermas develop along with existing skin diseases, such as eczema and psoriasis, or systemic diseases, for example, mycosis fungoides and blood diseases. The course of an erythroderma may be acute, subacute, or chronic.

Treatment is determined by the main cause. Desensitizing agents (calcium chloride, sodium thiosulfate) and antihistaminics (diphenyinhydramine hydrochloride, chloropyramine) are prescribed. Dietary restrictions are necessary.

REFERENCE

Mnogotomnoe rukovodstvo po dermato-venerologii, vol. 3. Moscow, 1964.

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References in periodicals archive ?

Tsubota A, Akiyama M, Sakai K, et al: Congenital ichthyosiform erythroderma mimicking ichthyosis bullosa of Siemens.

Inherited keratinization disorders/Kalitsal keratinizasyon bozukluklari

Staging and prognosis of mycosis fungoides * Stage Skin disease Adenopathy IA Patch/plaque (<10% BSA) - IB Patch/plaque (>10% BSA) - IIA Patches or plaques + IIB Tumors [+ or -] III Generalized erythroderma [+ or -] IVA Patch/plaque, tumors, or erythroderma [+ or -] IVB Patch/plaque, tumors, or erythroderma [+ or -] Lymph node Visceral Stage pathology involvement IA - - IB - - IIA - - IIB - - III - - IVA + - IVB + + Survival at Stage 10 years IA 100% IB 100% IIA 64% IIB 64% III 45% IVA Poor IVB Poor * From reference 11.

Diverse cutaneous manifestations associated with a single disease

Keratotic spines and Lesions appeared on the dorsa of the hands pits (15) and fingers and on the posterior neck of a 6-year-old boy who also had generalized erythroderma.

Hair loss and plaquelike skin lesions

It is interesting that our patient developed ocular symptoms 2 months after experiencing erythroderma.

Vogt-Koyanagi-Harada syndrome and ulcerative colitis

The compound, known as Glylorin(TM), entered phase III clinical trials in January 1996 for nonbullous congenital ichthyosiform erythroderma (n-CIE), and also is expected to be evaluated in the treatment of other less severe forms of the disease.

Glaxo Wellcome Obtains License For Investigational Compound To Treat Ichthyosis

A diffuse macular erythroderma mimicking sunburn rash was noted.

Severe eosinophilia during the course of toxic shock syndrome. (Letters to the Editor)

Nasdaq: CLGY; Warrants: CLGYW) announced today it had commenced Phase III clinical trials on Glylorin(TM) for the treatment of non-bullous congenital ichthyosiform erythroderma, a congenital skin disease which is a subtype of congenital primary ichthyosis.

CELLEGY BEGINS PHASE III TRIALS ON GLYLORIN(TM)

SAHA was shown to reduce the tumor burden and improve pruritus in CTCL patients, especially those with erythroderma and Sezary Syndrome.

Merck Announces Phase II Study Results of SAHA in Advanced, Refractory Cutaneous T-cell Lymphoma - CTCL - Patients

A 63-year-old white woman had generalized erythroderma in the spring of 1999.

Team D: pathology, allergy & immunology, dermatology, plastic & reconstructive surgery, and rheumatology

today announced the completion of a Phase II dose-ranging study of Glylorin(TM) (monolaurin) in patients with congenital ichthyosis erythroderma (CIE).

CELLEGY REPORTS PHASE II CLINICAL TRIAL RESULTS OF GLYLORIN(TM) FOR ORPHAN DRUG DESIGNATED INDICATION, CONGENITAL ICHTHYOSIS

When large numbers of the tumor cells are found circulating in the blood along with erythroderma and lymphadenopathy, the condition is called the Sezary syndrome.

Biomodulation of ONTAK Increases In Vitro Cytotoxicity in Leukemia and Lymphoma Cells

85] Cutaneous manifestations of the leukemias are varied, and additional skin findings include hemorrhagic lesions, generalized pruritus, exfoliative erythroderma, pyoderma gangrenosum, urticaria, erythema multiforme, erythema nodosum, panniculitis, hyperpigmentation, and morbilliform eruptions.