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Inflammation of the esophagus.



inflammation of the mucosa of the esophagus. Esophagitis may be an independent disease or, more often, a symptom of another disease of the esophagus, stomach, or other organ. The inflammation is frequently caused by chemical, mechanical, or thermal irritation of the esophagus; for example, it may be caused by eating very hot and spicy food.

Catarrhal, phlegmonous, necrotic, and other forms of esophagitis are distinguished based on the severity of the inflammatory changes. In severe cases the inflammatory process may extend to the muscular layer of the esophagus, and sometimes, to the surrounding mediastinal tissue, giving rise to mediastinitis. One form of the disease, peptic esophagitis, is caused mostly by a reflux of the acidic contents of the stomach into the esophageal lumen in cases of hiatus hernia. Peptic esophagitis is sometimes associated with the development of an ulcer in the esophageal wall.

The course of the disease may be acute or chronic. Chronic esophagitis is frequently caused by alcohol abuse or smoking. The symptoms include a burning sensation, retrosternal pain on swallowing, excessive salivation, and regurgitation of food. Esophagoscopy is sometimes used to diagnose the disease. Treatment is by diet (eliminating coarse, hot, and acidic foods), pain relievers, astringent and antispasmodic drugs, and, in some forms, antibiotics and surgery.


Vasilenko, V. Kh., A. L. Grebnev, and M. M. Sal’man. Bolezni pishchevoda. Moscow, 1971.


References in periodicals archive ?
Eozinofilik Ozofajit/Eosinophilic esophagitis nofil arasinda degisiklikler gosterebilmektedir (33).
Dr Souza, another of the study's authors, commented that "in animal models of reflux esophagitis designed to mimic the human disease, researchers hadn't looked at the early events in the development of esophageal injury.
Recent studies exploring elemental diets in children have found that these diets can lead to a complete amelioration of esophageal eosinophils, confirming that food allergies are related to eosinophilic esophagitis in at least some patients.
Elderly patients can attribute symptoms to "just indigestion" when there are other more serious diseases present (ie, angina, severe esophagitis, stricture, cancer).
The types of lesions discovered included those associated with erosive esophagitis, duodenal ulcers, colon cancer, and Crohn's colitis, Dr.
This may offer the first molecular explanation for why people with esophagitis should avoid alcoholic drinks, says Davis.
Maintenance therapy [] Symptoms without esophagitis [] Lifestyle modifications [] Antacids [] H2RAs [] Promotility agents [] Mild esophagitis [] Lifestyle modifications [] H2RAs twice daily [] Promotility agents [] Severe esophagitis [] Lifestyle modifications [] PPIs [] High-dose H2RAs with or without promotility agents [] Antireflux surgery [] Nissen fundoplication antireflux surgery
For the past decade, oral nystatin therapy has been considered effective in controlling Candida esophagitis (11).
paraesophageal hernia) or is complicated by severe GERD or esophagitis (inflammation of the esophagus).
potential causes of pain in the mid-lower chest, the physician can diagnose reflux esophagitis either through endoscopy (in which a tube is inserted into the esophagus for direct viewing of the affected area), or the socalled upper GI series.
It also reviews key players involved in the therapeutic development for Esophagitis.