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Any of a group of enzymes that catalyze the synthesis and hydrolysis of esters.



any of the enzymes of the hydrolase class that catalyze the cleavage of the ester bond in organic compounds. In the broad sense of the word, esterases include lipases, phosphatases, and sulfatases, in addition to esterases proper, among which are many specific enzymes, such as cholinesterase, chlorophyllase, tannase, and pectinase. Esterases are found in humans, animals, higher plants, and microorganisms. In humans and animals, they are found in pancreatic juice (pancreatic lipase, or steapsin), blood, and milk; they are also found in the liver, the intestinal walls, and various tissues.

References in periodicals archive ?
C1 esterase inhibitor[human]) in pediatric patients provided relief from symptoms of hereditary angioedema (HAE) attacks and reduced the rate of attacks.
C1 Esterase Inhibitor (Human), a pasteurized, nanofiltered, plasma-derived intravenous therapy, treats acute facial, abdominal and laryngeal hereditary angioedema (HAE) symptoms by providing C1-INH-deficient adult and adolescent patients with the missing human protein.
FDA-approved C1 esterase inhibitor therapy indicated for routine prophylaxis against angioedema attacks in adolescent and adult patients with hereditary angioedema (HAE), a rare, debilitating and potentially fatal disease.
In a poster entitled, 'Open-Label Use of Nanofiltered C1 Esterase Inhibitor (Human) (nf-C1 INH) for Treatment or Prophylaxis of Acute Attacks of Hereditary Angioedema (HAE) in Pregnant Subjects,' Dr.
C1 esterase inhibitor[human]) growth in North America; updates on launch progress and projections for Cinryze, Buccolam[sup.
In the interim, FDA indicated that studies of the combination of Cinryze (C1 esterase inhibitor[human]) and rHuPH20 were being placed on temporary clinical hold.
July 27, 2012 /PRNewswire/ -- ViroPharma Incorporated (Nasdaq: VPHM) today announced the publication of data demonstrating that routine prophylactic use of Cinryze (C1 esterase inhibitor[human]) provided effectiveness and maintained a generally favorable safety profile in the majority of treated subjects with hereditary angioedema (HAE).
In light of the August 9th PDUFA date for industrial scale expansion of Cinryze (C1 esterase inhibitor[human]), the company has chosen to align the two events.
NIMES, France -- Within the frame of its collaboration with Degussa, Proteus has discovered and developed a highly thermostable esterase biocatalyst from a Pyrococcus sp.
These test strips are the same as used in the Miditron but are supplied in a cassette holding 400 test strips for leukocyte esterase, nitrite, protein, glucose, ketones, urobilinogen, bilirubin, hemoglobin/myoglobin, and pH.
They've discovered that several strains have a unique, membrane-bound protein called esterase, which detoxifies some insecticides.