a-Aminoxylated ethyl acetoacetate
and indole was selected as model substrates to investigate the tandem reaction.
ABSTRACT: An environmentally benign approach for one-pot synthesis of 3,4-dihydropyrimidin-2-(1H)-ones derivative (DHPMs) using ethyl acetoacetate
, urea and benzyl alcohol instead of aldehyde under microwave cavity is described.
A series of compounds ethyl/methyl-4-(aryl)-6-methyl-2-oxo/thioxo-1, 2, 3, 4-tetrahydropyridimidine-5-carboxylate under investigation for acoustical parameters in the present paper was synthesized by the previously published method  they were synthesized by the reaction of ethyl acetoacetate
, urea /thiourea and p-chlorobenzaldehyde/Salicyldehyde/ furaldehyde by using solid supported K-10 Montmorillonite clay as a catalyst.
The ligand was synthesized by MCR (multi component reaction) of ortho toluidine, ethyl acetoacetate
and triethyl orthoformate and the condensed product was further cyclized in dowtherm A.
, methyl acetoacetate, dimethyl acetoacetamide, monomethyl aceto-acetamide, and acetoacetanilide are low-color copromoters for room-temperature cure of unsaturated polyesters.
Elaborating on the procedure of the research, Shaneghi reiterated, "First, we mixed ethanol and ethyl acetoacetate
together at the room temperature.
W e synthesized 5,6-dehydrokawain (1) and yangonin (4) via three steps from the dianion of ethyl acetoacetate
achieving a good yield and determined their conformations by high resolution NMR and x-ray crystallographic analysis.
Several dilithiated beta-ketoesters, such as ethyl acetoacetate
, and beta-diketones, such as 1-benzoylacetone, were condensed with polylithiated methyl 2-(aminoulfonyl)-benzoate to give C-acylated intermediates that were not isolated but cyclized directly to the 3-substiuted 1,2-benzisothiazole 1,1-dioxides.
Summary: Sodium bicarbonate was applied as catalyst for the synthesis of 3,3-bis(3-hydroxy-5-substituted-1H-pyrazol-4-yl)indolin-2-ones via the reaction of isatins, hydrazine hydrate and ethyl acetoacetate
or ethyl benzoylacetate.
We could achieve the synthesis of this compound in one step using 3hydroxybenzaldehyde, thiourea, ethyl acetoacetate
and SSA under the above mentioned reaction conditions.
, methyl acetoacetate, dimethyl acetoacetamide, monomcthyl aceto-acetainide, and acetoacetanilide are low-color copromoters for room-temperature cure of unsaturated polyesters.
In recent years, boric acid has gained special attention in organic synthesis for a number of synthetic transformations, such as Biginelli reaction , transesterification of ethyl acetoacetate
, aza Michael  and thia Michael addition , oxidation of sulphides , preparation of a- hydroxyamides , silylation of alcohols , synthesis of 1,5-benzodiazepine , benzimidazoles , N,N'-alkylidene bisamides , 1-amidoalkyl-2-naphthols  and 4H-isoxazol-5-ones .