A Typical Procedure for N-formylation of Amines with Ethyl Formate Promoted by H2SO4/Activated Charcoal System
In a round-bottom flask (10 mL) equipped with a magnetic stirrer and condenser, a solution of aniline (1 mmol, 0.093 g) in ethyl formate (2 mL, 0.025 mol) was prepared.
Equal amounts (40 [micro]L) of the sample (ethyl acetate extract), mixture of the sample with gallic acid, and only gallic acid were applied on a TLC plate (silica gel 60[F.sub.254]) (Merck, Germany) and developed in a previously saturated glass chamber (mobile phase of dichloromethane : ethyl formate
: formic acid (5:5:0.2)) at room temperature.
"There has been a spike in people taking something called ethyl formate
. We are seeing people with serious problems because of this."
However, in their search for amino acids, the scientists stumbled onto a substance called ethyl formate. This is the chemical compound responsible for giving raspberries their distinct taste.
Arnaud Belloche of Cornell University reportedly said, "It does happen to give raspberries their flavour, but there are many other molecules that are needed to make space raspberries." What is even more fascinating is that ethyl formate has another unique trait, it smells like rum!
According to a report in the Guardian, astronomers searching for the building blocks of life in a giant dust cloud at the heart of the Milky Way have concluded that it contains the chemical ethyl formate
, which gives raspberries their flavour and smells of rum.
Glycerol, diethanol-amine, and ethyl formate
(analytical grade) were purchased from Tianjin Chemical Reagent Ltd.
The molecules, ethyl formate
and n-propyl cyanide, were detected in the star-forming region of space known as Sagittarius B2 and represent two different types of molecule - the esters and alkyl cyanides - which were found in a giant dust cloud at the heart of our galaxy.
In the presence of carbonyl containing molecules such as ethyl formate
and methyl pyruvate, the Laval group has isolated and observed multiple hydrogen bonds between the two adsorbed species in which the aromatic C-H bonds act as hydrogen bond donors.
The two compounds having the highest mass flowrates (methyl acetate and ethyl formate
) are never generated alone, therefore, using their values would result in an over conservative design.
Berlin, April 21 (ANI): Scientists from the Max Planck Institute for Radio Astronomy in Bonn, Germany, Cornell University, USA, and the University of Cologne, Germany, have detected two of the most complex molecules yet discovered in interstellar space: ethyl formate
and n-propyl cyanide.