The nuclei possess fine granulated euchromatin
and heterochromatin with the latter adjacent to the nuclear envelope (Fig.
Sertoli cells with euchromatin
nuclei and intact cytoplasmic organelles were seen.
As H3K9 is primarily found in the silenced region within the euchromatin
, G9a has been implicated to play a role in the silencing of gene expression [28-30].
Z in chromatin is implicated in transcriptional activation and euchromatin
maintenance (Redon et al.
The electron micrographs, of the untreated mouse mammary tumor cells were bounded by delicate plasma membranes and displayed large nuclei containing uniformly distributed euchromatin
and conspicuous marginal heterochromatin abutting the nuclear membrane and a prominent nucleolus (Figs.
More importantly, this euchromatin
state is maintained through the expression of CDX2 and CREBBP.
1998), the GABA-ir neurons could be classified as type 1 neuronal cells (NR1), which are the largest neurons having an oval or pyramidal shape (diameter, about 10 x 20 [micro]m), and contain an oval-shaped nucleus with complete euchromatin
, and large nerve process.
Silent genes tend to be packaged as heterochromatin whereas active, functional genes are in euchromatin
High content of euchromatin
of nucleus and extended network of hyperplastic tubules of granular endoplasmic reticulum (GER) with flocculent material in the lumen showed a high level of protein synthesis.
In contrast, DNA in euchromatin
is susceptible to nuclease digestion and is unavailable for qPCR.
Key epigenetic players are DNA methylation and histone post-translational modifications, which interplay with each other, with regulatory proteins and with non-coding RNAs, to remodel chromatin into domains such as euchromatin
, constitutive or facultative heterochromatin and to achieve nuclear compartmentalization (1).
The distribution of mitomycin C-induced sister chromatid exchanges in the euchromatin
and heterochromatin of the Indian muntjac, Chromosoma 64: 97-107.