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Erythroderma or exfoliative dermatitis is caused by various diseases including eczema of various subtypes, psoriasis, lymphoma, leukaemia, pemphigus foliaceus, lichen planus, dermatophytosis, crusted scabies, drugs including phenylbutazone, phenytoin, carbamazepine, gold salts, lithium, cimetidine, hereditary disorder like ichthyosiform erythroderma and pityriasis rubra pilaris also can lead to exfoliative dermatitis.
It consists of exfoliative dermatitis, generalized lymphadenopathy, hepatosplenomegaly, fever and hepatitis.7
Exfoliative dermatitis: its etiology and prognosis.
Erythroderma, also called exfoliative dermatitis, is a rare skin condition, sometimes presents as waxing and waning pattern.
PHT-induced cutaneous lesions may be restricted to maculopapular rash [Figure 1] or cutaneous nodules or consist of a generalized exfoliative dermatitis or TEN.[14] PHT may cause pseudolymphoma syndrome.[15] CBZ can cause maculopapular rashes, DRESS [Figure 2], urticaria, photosensitivity reactions, exfoliative dermatitis, erythema multiforme, SJS, and TEN [Figures 3 and 4].
Islam S et al., (19) conducted a study on biochemical changes in exfoliative dermatitis. Hyponatremia and hypokalemia were observed in 18% and 12% respectively in the study.
And if the patient is not seen in the early phase of the reaction, it may evolve into a chronic exfoliative dermatitis, she added.
Troilius reported five cases of eczema which mainly affected the normal, nonhemiplegic side.2 Thomsen reported a patient who developed Beau's lines on the fingernails of his non paretic side following generalized exfoliative dermatitis.3
Exfoliative dermatitis was seen in one patient secondary to rifampicin, administered as a part of ATT for pulmonary Kochs.
i) Erythroderma (exfoliative dermatitis) Erythema and scaling involving most of the body surface area (90 Percent), develops either de novo (primary or idiopathic) or as a progression of a pre-existing skin disease (secondary).
Dapsone hypersensitivity syndrome, granulomatous hepatitis, exfoliative dermatitis, leprosy, dapsone.