exonuclease

(redirected from Exonuclease III)
Also found in: Dictionary, Thesaurus, Medical, Wikipedia.

exonuclease

[¦ek·sō′nü·klē‚ās]
(biochemistry)
Any of a group of enzymes which catalyze hydrolysis of single nucleotide residues from the end of a deoxyribonucleic acid chain.
Mentioned in ?
References in periodicals archive ?
It was demonstrated that fpg probes are less sensitive (10"1 target molecules detected) than exo probe assays (10 target molecules detected), suggesting that the Fpg nuclease has slower kinetics in realtime detection than that of exonuclease III (14).
Determinants in nuclease specificity of Ape1 and Ape2, human homologues of Escherichia coli exonuclease III. J Mol Biol 318:853-868.
We added 10 [micro]L of exonuclease mixture to the reactions for final concentrations of 67 mM Tris-HCl (pH 9.0), 50 mM KCl, 3.7 mm Mg[Cl.sub.2], 0.1 [micro]g/[micro]L bovine serum albumin, and 0.5 U/[micro]L exonuclease I and exonuclease III (New England Biolabs).