extracellular matrix

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extracellular matrix

[¦ek·strə¦sel·yə·lər ′mā·triks]
(cell and molecular biology)
A filamentous structure that is attached to the outer cell surface and provides anchorage, traction, and positional recognition to the cell.
(histology)
A filamentous structure of glycoproteins and proteoglycans that is attached to the cell surface and provides cells with anchorage, traction for movement, and positional recognition. Abbreviated ECM.
References in periodicals archive ?
In pathologies where fibrosis is a feature, there is an increased deposition of extracellular matrix proteins, including collagens that dramatically limit tissue function.
It involves fibroblasts, inflammatory and endothelial cells, and extracellular matrix proteins.
The acellular tissue matrices are biocompatible, slowly degraded upon implantation and are replaced and remodelled by the extracellular matrix proteins synthesized and secreted by in growing host cells, which reduce the inflammatory response (Pariente et al.
The spectrum of known Matriptase substrates includes extracellular matrix proteins, cell adhesion molecules, ion channels, growth-factor-like proteins and other proteases.
Differential expression of extracellular matrix proteins and integrins in hepatocellular carcinoma and chronic liver disease.
Instead of using the stem cells to generate single heart cells in a dish, the cells were grown on chips lined with human extracellular matrix proteins that mimic their natural environment, tricking the cells into joining together as they would if they were forming a diseased human heart.
Delicate strands of extracellular matrix proteins such as collagen and elastin are barely visible on mammo grams of healthy breasts, says Thea Tlsty, a molecular pathologist at the University of California, San Francisco.
Under pathological conditions, increased ROS bioactivity lead to endothelial dysfunction, increased contractility, vascular smooth muscle cell (VSMC) growth, lipid peroxidation and increased deposition of extracellular matrix proteins, which were important factors in hypertensive vascular and renal damage (Diep et al.
Initially, PRIME-XV products will comprise of a serum-free medium for the expansion of human mesenchymal stromal/ stem cells (MSCs), biopreservation solutions and extracellular matrix proteins.
GINTUIT is a cellular sheet that contains human fibroblasts, keratinocytes, human extracellular matrix proteins and bovine collagen.

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