Sir James Paget

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Paget, Sir James

(păj`ĭt), 1814–99, British surgeon and pathologist. He taught and practiced at St. Bartholomew's Hospital, London, and cataloged the museums of St. Bartholomew's and of the Royal College of Surgeons. He was a skilled diagnostician and an authority on diseases of the bones and joints. His works include Lectures on Tumours (1851) and Lectures on Surgical Pathology (1853).
References in periodicals archive ?
Ozawa et al., "Androgen receptor, androgen-producing enzymes and their transcription factors in extramammary Paget disease," Human Pathology, vol.
Terada, "Extramammary paget disease of signet ring cell carcinoma type: a case report," American Journal of Dermatopathology, vol.
Extramammary Paget Disease.--Extramammary Paget disease can be either primary or secondary.
The main differential diagnosis of pagetoid dyskeratosis includes extramammary Paget disease, pagetoid spread of carcinoma cells, pagetoid Bowen disease, and pagetoid melanoma.
In contrast to extramammary Paget disease of other sites, perianal Paget disease (PPD) has a high frequency of associated regional internal cancers, most commonly rectal adenocarcinoma.[1-4] Immunohistochemical stains for gross cystic disease fluid protein 15 (GCDFP-15) and cytokeratins (CKs) 7 and 20 have been found to be useful in separating those cases of PPD that are associated with rectal adenocarcinoma from those that are not.