actin

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Related to F-actin: phalloidin, G-actin, Vinculin

actin,

a protein abundantly present in many cells, especially muscle cells, that significantly contributes to the cell's structure and motility. Actin can very quickly assemble into long polymer rods called microfilaments. These microfilaments have a variety of roles—they form part of the cell's cytoskeleton, they interact with myosinmyosin
, one of the two major protein constituents responsible for contraction of muscle. In muscle cells myosin is arranged in long filaments called thick filaments that lie parallel to the microfilaments of actin.
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 to permit movement of the cell, and they pinch the cell into two during cell division. In muscle contraction, filaments of actin and myosin alternately unlink and chemically link in a sliding action. The energy for this reaction is supplied by adenosine triphosphateadenosine triphosphate
(ATP) , organic compound composed of adenine, the sugar ribose, and three phosphate groups. ATP serves as the major energy source within the cell to drive a number of biological processes such as photosynthesis, muscle contraction, and the synthesis of
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.

actin

[′ak·tən]
(biochemistry)
A muscle protein that is the chief constituent of the Z-band myofilaments of each sarcomere.
References in periodicals archive ?
FITC-phalloidin, applied for conjugation to F-actin, was incubated with the podocytes according to the manufacturer's protocol (YEASEN, Shanghai, China).
Effect of myosin on conformational changes of F-actin in thin filament in vivo induced by calcium ions.
(1) 14-3-3 proteins facilitate targeting of NMDARs to the postsynaptic density, thereby regulating long-term potentiation; (2) 14-3-3 proteins might promote spinogenesis by facilitating F-actin formation.
Mutations at this location may have a disruptive effect on the ABD interface, thereby affecting the activity of ABDs binding to F-actin [7, 24, 25].
Previously it was mentioned the F-actin and G-actin.
Two months later, nevertheless, she again developed symptoms associated with serum transaminases elevation, the same liver injury phenotype from previous DILI, but, at this time, with hypergammaglobulinaemia and positive autoantibodies, namely, ANA, ASMA, pANCA, and F-actin, raising the hypothesis ofdrug-induced autoimmune hepatitis [11, 12].
General overview of tubulin or F-actin staining is shown in the left columns while an enlarged view of a corresponding image is given in the right columns for a better detail.
TRAP staining and F-actin ring formation were used to assay osteoclastogenesis.
The GLE suppressed the TGF-[beta]1 -induced morphological changes and the changes in cadherin expression, and also inhibited the formation of F-actin stress fibers, which are a hallmark of EMT.
Phalloidin conjugated with a derivative of rodamin was used to stain the filamentous actin (F-actin).
This is particularly prominent when mutations involve the N-terminal actin-binding-domain or the Cys-rich domain affecting the binding of dystrophin to F-actin or [beta]-dystroglycan, respectively.