The following study will assess aqueous humor prostaglandin E2 (PGE2) concentrations after FLAC (lens fragmentation may influence the inflammatory response and hence prostaglandin production due to cataract density disparities between the eyes) in patients who were pretreated with topical ketorolac compared with patients who did not receive NSAID pretreatment.
Mean concentration of aqueous humor PGE2 after FLAC was 392.16 [+ or -] 162.00 pg/ml (range: from 202.04 to 713.71 pg/ml) and 622.63 [+ or -] 331.84 pg/ml (range: from 310.09 to 1469.74 pg/ml) for groups 1 and 2, respectively.
A recent study from our institute demonstrated that patients receiving a 3-day topical regimen of ketorolac prior to FLAC better retained their mydriasis after the laser treatment .
The current study evaluated aqueous humor concentration of PGE2 after FLAC (only capsulotomy was performed), using the same laser platform and the same settings for capsulotomy creation in all eyes included.
Despite the above limitations, we demonstrate that a 3-day (4 times per day) topical use of an NSAID agent (ketorolac) prior to FLAC seems to prevent excessive release of PGE2 in the anterior chamber.
As shown in Figure 4(a), significant heterogeneity was observed among the studies evaluating UDVA ([I.sup.2] = 98%, P <0.00001) and no significant difference in UDVA was observed between FLACS and CPCS (MD = -0.01, 95% CI: -0.13-0.10, P = 0.80).
As shown in Figure 5, significant heterogeneity was calculated among studies evaluating refractive outcomes ([I.sup.2] = 73%, P = 0.05) and FLACS that showed MAE in FLACS group was significantly lower than that in CP group (MD = -0.17, 95% CI: -0.32-0.02, P = 0.02).
reported that pupil miosis occurred in 1 eye and mild subconjunctival hemorrhage occurred in 5 eyes after FLACS .
has suggested that FLACS is superior to CPCS for the reduction of mean phaco energy and effective phacoemulsification time .
It has been previously suggested that FLACS has a lower complication rate compared with CPCS .
Do not attempt the flic and flac
until you have mastered all the preparatory skills and your coach is there to help you.