immunoassay

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Immunoassay

An assay that quantifies antigen or antibody by immunochemical means. The antigen can be a relatively simple substance such as a drug, or a complex one such as a protein or a virus. See Antibody, Antigen

The reactants are first mixed so that a varying quantity of one (A) is added to a constant amount of the other (B). The formation of an immune (antigen-antibody) complex is measured as a function of the varied reactant (A). The result is represented by a “standard curve” for reactant A. An unknown sample is tested by adding it to reactant B. The extent of the measured change is referred to the standard curve, and thereby is obtained the amount of reactant A which produces a comparable change. The amount is represented as the content of reactant A in the unknown sample. See Immunofluorescence, Immunology, Radioimmunoassay

immunoassay

[‚im·yə·nō′a‚sāy]
(immunology)
A laboratory detection method that uses antibodies to react with specific substances.
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[3] Nonstandard abbreviations: HDMTX, high-dose methotrexate; MTX, methotrexate; [CPDG.sub.2], carboxypeptidase G2; DAMPA, 2,4-diamino-[N.sup.10]-methylpteroic acid; FPIA, fluorescence polarization immunoassay; LC-MS/MS, liquid chromatography-tandem mass spectrometry.
Difficulty measuring methotrexate in a patient with high-dose methotrexate-induced nephrotoxicity
We observed statistically significant increases in serum digoxin concentrations in the presence of various ginsengs when FPIA was used.
Interference of Asian, American, and Indian (Ashwagandha) ginsengs in serum digoxin measurements by a fluorescence polarization immunoassay can be minimized by using a new enzyme-linked chemiluminescent immunosorbent or turbidimetric assay
In surveys 2 and 3, tHcy was measured by the FPIA method 7 of 23 and 6 of 17 times, respectively.
Interlaboratory variation of plasma total homocysteine measurements: results of three successive homocysteine proficiency testing surveys
Response of AxSYM FPIA assay for amphetamines after addition of heptaminol to drug-free urine.
Heptaminol interferes in the AxSYM FPIA amphetamine/methamphetamine II assay
We can also exclude that the higher MEGX concentrations observed in uremic patients were the result of positive interferences with the TDx FPIA by substances that had accumulated in uremic plasma because the predose (0 min) value was subtracted from values obtained at the various postinjection times.
Effects of chronic renal failure and hemodialysis on the Monoethylglycinexylidide liver function test
Abbreviations: EPIC: the European Prospective Investigation into Cancer and Nutrition; vs: versus; M: male; F: female; PB: population-based; HB: hospital-based; HPLC: High Performance Liquid Chromatography; GC-MS: gas chromatography-mass spectrometry; FPIA: fluorescence polarization immunoassay.
Homocysteine and Digestive Tract Cancer Risk: A Dose-Response Meta-Analysis
The analysis of cortisol was performed on an Architect i2000[TM] immunochemistry analyzer (Abbott, Chicago, IL, USA) using the fluorescence polarization immunoassay FPIA (Abbott).
Selected Biomarkers Correlate with the Origin and Severity of Sepsis
The effects of adulterating agents on FPIA analysis of urine for drugs of abuse.
Commercial herbal medicines used as African traditional medicines: Ngoma Herbal Tonic Immune Booster interferes with a rapid urine drug screening test
Serum hormone concentration for qualitative determination of GH was done by Enzyme Amplified Sensitivity Immunoassay, T3 was done by using Micro Particle Enzyme Immuno Assay (MEIA), while T4 was analyzed using Fluorescence Polarization Immunoassay (FPIA).
Changes in Kisspeptin, Growth and Thyroid Hormones in Thalassemic Patients of Pubertal Age Group
The plasma total homocysteine levels were measured with fluorescence polarization immunoassay, FPIA in the IMX System.
Evaluacion de factores geneticos y bioquimicos en individuos con sindrome coronario agudo
Serum Hcy levels were determined by FPIA method in IMX apparatus [38].
Plasma and Aorta Biochemistry and MMPs Activities in Female Rabbit Fed Methionine Enriched Diet and Their Offspring
Total homocysteine concentration in plasma was determined by an immunochemical method with the fluorescence polarization immunoassay (FPIA) using an IMx analyzer and special ABBOTT sets.
Abnormal Biomarkers of Homocysteine Metabolism in Neonates with Conotruncal Heart Defects

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