factor VII

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Related to Factor VIIa: factor VIII, Novoseven

factor VII

[′fak·tər ′se·vən]
(biochemistry)
A procoagulant, related to prothrombin, that is involved in the formation of a prothrombin-converting principle which transforms prothrombin to thrombin. Also known as stable factor.
References in periodicals archive ?
Recombinant factor VIIa for the management of severe hemorrhages in patients with hematologic malignancies.
Randomized, prospective clinical trial of recombinant factor VIIa for secondary prophylaxis in hemophilia patients with inhibitors.
For patients with high titer inhibitor, APC or Recombinant Factor VIIa should be employed.
Factor VIIa is a naturally occurring protein that plays an important role in the coagulation cascade.
GTC, together with its collaboration partner LFB Biotechnologies, has established the transgenic rabbit production system for its recombinant form of human coagulation factor VIIa (rhFVIIa) which is being developed for the treatment of patients with hemophilia.
Tissue factor- and factor X-dependent activation of protease-activated receptor 2 by factor VIIa.
Key Words: recombinant factor VIIa, Crohn disease, surgery, bleeding, hemorrhage
Concentrations of the following markers were determined as described previously (8,10): apoB, total cholesterol, apoAI, HDL, triglycerides, LDL peak particle diameter, glucose, insulin, body mass index (BMI), plasminogen activator inhibitor-1, lipoprotein(a), C-reactive protein (CRP), von Willebrand factor antigen, fibrinogen, D-dimer, factor VII, and factor VIIa.
Other antithrombotic agents being evaluated include oral heparins; other direct thrombin inhibitors like lepirudin, bivalirudin, and argatroban; defibrinating agents such as ancrod; anti-inflammatory agents such as P-selectin inhibitors; Factor VIIa inhibitors; tissue factor pathway inhibitor; and activated protein C.
Relationships between homocysteine, factor VIIa, and thrombin generation in acute coronary syndromes.