factor VII

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Related to Factor VIIa: factor VIII, Novoseven

factor VII

[′fak·tər ′se·vən]
(biochemistry)
A procoagulant, related to prothrombin, that is involved in the formation of a prothrombin-converting principle which transforms prothrombin to thrombin. Also known as stable factor.
References in periodicals archive ?
They were randomized to infusion of recombinant factor VIIa (a potent procoagulant agent) or to the usual care and showed no benefit following such treatment (30).
Recombinant factor VIIa for the prevention and treatment of bleeding in patients without haemophilia.
Randomized, prospective clinical trial of recombinant factor VIIa for secondary prophylaxis in hemophilia patients with inhibitors.
One study of rivaroxaban-induced bleeding in a rabbit model reported that a 4-factor PCC and recombinant factor VIIa (rFVIIa) improved coagulation laboratory studies but did not significantly reduce bleeding.
Autologous Transfusion, Recombinant Factor VIIa, and Bloodless Medicine.
The facility would house genetically engineered rabbits raised to produce milk loaded with Factor VIIa, a blood-clotting agent for patients with hemophilia.
DSS with liver failure was diagnosed and treated with intravenous fluid, sodium bicarbonate, omeprazole, fresh frozen plasma, platelet transfusion, vitamin K, and recombinant factor VIIa concentrate (NovoSeven; Novo Nordisk, Bagsvaerd, Denmark).
Asi mismo, ha surgido un dato adicional respecto a las secuencias de activacion, acerca del factor VIIa, el cual no solo activa al X como era previamente conocido, sino tambien al IX, lo que establece un enlace entre las dos secuencias, antes consideradas separadas [11].
The role of recombinant factor VIIa in liver transplantation.
(4) Free TFPI directly inhibits factor Xa, (5) whereas surface-bound TFPI on endothelial cells inhibits TF and factor VIIa complex.