Fanconi's syndrome


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Related to Fanconi's syndrome: Fanconi's anemia

Fanconi's syndrome

[′fäŋ·kō·nēz ′sin‚drōm]
(medicine)
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This scenario generated a high cadmium intake by that population, which has led to the development of the Fanconi's syndrome, generating osteomalacia in a number of inhabitants [22].
Shoback, "Fanconi's syndrome in HIV+ adults: Report of three cases and literature review," Journal of Bone and Mineral Research, vol.
Elevated serum 1,25-dihydroxyvitamin D concentrations in siblings with primary Fanconi's syndrome. N Engl J Med 1988;319:845-849.
Previously, there have been a few case reports describing the reversal of ADV and TDF-related Fanconi's syndrome after TDF withdrawal in patients with CHB [12, 26].
Though systemic manifestations are rarely seen in Sjogren's disease yet complications like hypokalemia or Fanconi's syndrome may progress to life threatening renal impairment given the progressive nature of the disease.
Class-related, serious and common adverse effects of frequently used antiretrovirals Class AEs Serious AEs Nucleos(t)ide reverse transcriptase inhibitors (NRTI) Tenofovir Hyperlactataemia and Renal failure, (TDF) lactic acidosis, with Fanconi's syndrome hepatic steatosis Lamivudine Lipodystrophic changes (3TC) and emtricitabine (FTC) Zidovudine Anaemia, leuco-or (AZT) neutropenia Abacavir (ABC) Drug hypersensitivity reaction Stavudine(d4T) Didanosine Pancreatitis (ddI) Non-nucleoside reverse transcriptase inhibitors (NNRTI) Efavirenz Drug hypersensitivity Rare (0.2%) but severe (EFV) rash(NVP 24%, EFV 18% ); neuro-psychiatric Stevens-Johnson effects (depression, syndrome(NVP 0.3%, EFV delusions).
It is thought that one mechanism through which they cause acute tubular necrosis (and Fanconi's syndrome) is tubular mitochondrial toxicity.
Lambda-light-chain nephropathy with Fanconi's syndrome. Arch Pathol Lab Med.