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The infection of humans with Fasciola hepatica.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.



a helminthiasis of animals and man; one of the trematodiases. It is caused by the common liver fluke and giant liver fluke, which parasitize man, cattle, sheep, swine, and other animals. The eggs are deposited mainly in the bile ducts of the liver and gall-bladder and are later excreted with the feces. The flukes continue their cycle of development in water and in snails, their intermediate hosts. Infection occurs when the larvae are swallowed with water and plants. In man, a fever develops within two to four weeks, together with a cough and skin eruptions. The liver enlarges and becomes tender. Acute manifestations gradually subside and the disease becomes chronic, a condition marked chiefly by digestive disorders and enlargement and tenderness of the liver.

Fascioliasis of animals occurs worldwide and may be acute or chronic. In the USSR it affects cattle and other bovines and camels, horses, and hares. The animals are infected in pastures. Hepatitis develops and results in impaired metabolism. The parasites’ toxins alter the morphological and chemical composition of the blood. Infected animals manifest loss of appetite, diarrhea, debilitation, and liver enlargement. Milk secretion is reduced in cows. In sheep, severe infestation is fatal.

In man, fascioliasis is treated with Chloxyl or emetine; in animals it is treated with Hexychol, bithionol, or carbon tetrachloride. The disease is prevented in man by boiling or filtering drinking water. It is prevented in animals by changing pastures, exterminating snails, and carrying out other sanitary measures.


Skriabin, K. I. Trematody zhivotnykh i cheloveka, vol. 2. Moscow-Leningrad, 1948.
Demidov, N. V. Fastsiolez zhivotnykh. Moscow, 1965.


The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
Effect of fascioliasis on hematological, serum biochemical and histopathological changes in sheep.
Hepatobiliary fascioliasis in non-endemic zones: a surprise diagnosis.
Ashrafi, A Survey on Human and Animal Fascioliasis And Genotypic and Phenotypic Characteristics of Fasciolids and their Relationship with Lymnaeid Snails in Gilan Province [Ph.D.
Studies on the prevalence and laboratory transmission of fascioliasis in animals in the Kashmir valley.
Patients with fascioliasis received myrrh extract at a dose of 10 mg/kg, one hour before breakfast for six consecutive days.
Singh, "The effect of abiotic factors on the toxicity of cypermethrin against the snail Lymnaea acuminata in the control of fascioliasis," Journal of Helminthology, vol.
Comparative studies on efficacy of ethanolic extracts of Calligonum comosum plant and triclabendazole (TCBZ)" Fasinex on treatment of fascioliasis in goats in Taif Governorate.
A wide variety of parasites can result in biliary tract infection; these include fascioliasis, schistosomiasias, clonorchiasis, ascariasis and echinoccoccosis.
Rashwan, "Oxygen free radical and nitric oxide production in single or combined human schistosomiasis and fascioliasis," Journal of the Egyptian Society of Parasitology, vol.
Little research has been done with free-floating metacercariae, but in human fascioliasis, certain patients have no other reported routes of infection other than ingestion of free-floating metacercariae (Mas-Coma 2004, Morley 2015).