Administration of HCD to the rats for period of 8 weeks has caused an early stage of atherosclerosis indicated by fatty streaks
evidence in the tunica media (Fig.
Atherosclerosis is the net result of the interplay among increased intravascular inflammation, endothelial dysfunction, and a host of risk factors (including elevated LDL-C levels) that initiate a cycle of lipid accumulation in the subendothelial space and subsequently lead to fatty streak
and plaque formation, plaque rupture and repair, thrombosis, and progressive stenosis.
White cells congregate at the site of the injury, becoming engorged with fat molecules and forming the first signs of atherosclerosis--the fatty streaks
that develop as early as the teenage years (SN: 1/20/90, p.
Most of the cholesterol in a fatty streak
lesion is not in the muscle [of the artery wall], but in cells that come from circulating monocytes," says Steinberg.
And half of kids now have fatty streaks
in their arteries and that is literally the early stage of heart disease.
90) Fuchs et al modified Goutallier's original classification scheme of fatty infiltration to MRI--describing the proportion of fatty streaks
and replacement relative to muscle.
South African studies indicated that early lesions such as fatty streaks
were common in black South Africans, but levels of more advanced lesions were lower than those reported for white South Africans, black and white Americans, and European populations.
A glass a day can protect your heart by stopping the production of endothelin-1, responsible for the fatty streaks
Furthermore, several studies have shown that fetuses and children born of hypercholesterolemic mothers have an increased incidence of fatty streaks
in the aorta.
The fruit also hampers hardening of the arteries by fatty streaks
along blood vessel walls (arteriosclerosis) by helping to stop high cholesterol.
pneumoniae antigens or DNA in intimal thickening and fatty streaks
of young adults and Alaskan Natives (the latter group at low risk for coronary atherosclerosis) supports an early microbial role in pathogenesis (30).
If you eat lots of greasy foods, ugly fatty streaks
may already be building up in your arteries.