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Related to Fc fragment: Surface immunoglobulin


A functional language.

["FC Manual", L. Augustsson, Memo 13, Programming Methodology Group, Chalmers U, Sweden 1982].
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The density of luminous power, also called illumination. One lumen of luminous flux, uniformly incident on 1 square foot of area, produces an illuminance of 1 footcandle; in SI units, one lumen of luminous flux, uniformly incident on 1 square meter of area, produces an illuminance of 1 lux.
McGraw-Hill Dictionary of Architecture and Construction. Copyright © 2003 by McGraw-Hill Companies, Inc.


(1) See Fibre Channel.

(2) (File Compare) An external DOS/Windows command that compares the content of two files. The following example compares the text files 1.TXT and 2.TXT. See file compare and Comp.
fc 1.txt 2.txt     blank areas
                     must match

  fc 1.txt 2.txt /w  blank areas do not
                     have to match

  fc 1.txt 2.txt /a  show only start and
                     end of mismatches

Text files are compared line by line, and discrepancies are displayed as follows:
***** first file
   ***** second file

Binary files, such as .EXE, .COM, .SYS, .OBJ, .LIB and .BIN, are compared byte for byte. To compare program files ABC.EXE and XYZ.EXE, type:
fc abc.exe xyz.exe

Binary file discrepancies are shown as follows. The AAAAAA is the hexadecimal location of the mismatched bytes, and the two BB's are the bytes (in hex) from the two files:
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References in periodicals archive ?
[1-3] Material used for this study contained a small fraction of free Fc fragment. Triple-angle light scattering data indicated that the Fab fragment of NISTmAb sample was in a monomeric state [2, 3].
In future, IVIG preparations containing a higher proportion of Fc fragments with terminal sialic acid residues may be even more effective.
Moreover, while egg proteins can trigger allergic reactions in some people, and the egg antivenins still retain their Fc fragments, the Wisconsin team anticipates no serious reactions to their product.
In this study, we have fused the extracellular domain of CTLA-4 to the Fc fragment of the human IgG1 antibody.
[4] Human genes: GALC, galactosylceramidase; ACADM, acyl-CoA dehydrogenase, C-4 to C-12 straight chain; ACADVL, acyl-CoA dehydrogenase, very long chain; GALT, galactose-1-phosphate uridyl transferase; PAH, phenylalanine hydroxylase; FCGR2A, Fc fragment of IgG, low affinity IIa, receptor (CD32); RPP30, ribonuclease P/MRP 30kDa subunit.
In intact antibodies, that amino acid portion -- called the Fc fragment -- normally mediates two powerful immune responses: It helps killer white blood cells recognize and ingest antibody-bound foreign invaders and it triggers a process known as complement activation that destroys those invaders by chemical dissolution.
Human Del-1, ICAM-1 fused to the Fc fragment of IgG (ICAM-1-Fc), and Fc protein control were purchased from R&D Systems, whereas Del-1-Fc was prepared in our laboratory as follows.
Because rhP/Fc is conjugated with an Fc fragment of IgG, to evaluate the concentrations of rhP/Fc, we used a colorimetric Fc quantification assay set generally used to estimate IgG concentration in serum.
[4] Human genes: IGHG1 human IgG1 heavy chain constant region; IGHG4 human IgG4 heavy chain constant region; and IGHE, human IgE heavy chain constant region; FCERIA, Fc fragment of IgE, high affinity I, receptor for; alpha polypepfide; FCER1G, Fc fragment of IgE, high affinity I, receptor for; gamma polypepfide; MS4A2, membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for beta polypeptide).
Thirteen samples were found to contain heterophilic antibodies binding to the [F(ab').sub.2] fragment, whereas the remaining 331 samples contained heterophilic antibodies directed against the murine Fc fragment.
Humanization of animal antibodies (15) and modification of assay antibodies by removal of the Fc fragment (16) are well-known methods that often dramatically reduce interference.
Initial studies showed that this interference mostly could be solved by the removal of the Fc fragment from the capture antibody, an indication of the presence of heterophilic antibodies.