Fibroadenoma


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fibroadenoma

[¦fī·brō‚ad·ən′ō·mə]
(medicine)
A benign tumor containing both fibrous and glandular elements.

Fibroadenoma

 

a mature benign tumor of connective and glandular tissues. A fibroadenoma develops in organs with a glandular structure, such as the breast and the prostate. It grows slowly, is clearly demarcated from the surrounding tissues, and is often encapsulated. The symptoms depend on the site: moderate tenderness of the breast if the mammary gland is affected and difficulty of urination, including acute retention of urine, if the prostate is involved. Malignant degeneration is possible. Fibroadenomas are treated surgically.

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1] It is difficult to distinguish from fibroadenomas, while malignant cystosarcoma phyllodes can grow in size quickly and metastasize early.
6) For instance, in an evaluation of several cases of primary osteosarcoma of the breast, Silver and Tavassoli found the mammographic impression to be that of a benign fibroadenoma in 33% of patients.
16% (47/120) patients with fibroadenoma followed by FCD seen in about 30.
While fibroadenomas cannot become cancerous, large fibroadenomas can potentially hamper the detection of other breast lumps that might be cancerous.
8 Diameter [mm] n Lesion Inflammatory CA 1 Fibroadenoma 41 Ductal CA In Situ 5 Invasive Ductal CA 49 Invasive Lobular CA 3 Medullar CA 2 Papillary CA 2 Tubular CA 1 Location Lower Outer Quadrant 18 Lower Inner Quadrant 7 Upper Outer Quadrant 37 Upper Inner Quadrant 11 Retroareolar area 31 Breast Side Right 58 Left 46 Avg[+ or -]Sd Age [years] 48.
Differential diagnosis of tubular adenomas includes malignancy and noncalcified fibroadenoma.
Objective: The aim of this study was to evaluate the performance of ultrasound (US) guided Vacuum Assisted Biopsy (VAB) in the therapeutic excision of breast fibroadenomas.
The primary outcome was measurement of fibroadenoma volume using ultrasound examinations after 6 months intervention.
Cellular fibroadenoma and juvenile fibroadenoma are common benign biphasic tumors recognized as distinct entities; the terms have been used interchangeably.
Fibroadenoma was the most frequently (N = 438) diagnosed lesion on FNA with maximum (N = 435) patients between 16 and 30 years.
In view of great age variety in group of healthy donors and groups of breast cancer and fibroadenoma patients, the comparisons were performed between age-matched groups.
National Cancer Centre Singapore, Duke-NUS Graduate Medical School Singapore, and Singapore General Hospital, made a seminal breakthrough by using advanced DNA sequencing technologies to identify a critical gene called MED12 that was repeatedly disrupted in nearly 60 percent of fibroadenoma cases.