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Related to Fibroblasts: Chondroblasts, Myofibroblasts


A stellate connective tissue cell found in fibrous tissue. Also known as a fibrocyte.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.



the basic cellular unit of connective tissue in man and other vertebrates. Fibroblasts produce fibers and the ground substance of connective tissue. They are converted to fibrocytes as a result of differentiation.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
Human keratinocytes and fibroblasts were cultured from the foreskin (Lan et al., 2014).
YAP shRNA-transfected and control shRNA-transfected cardiac fibroblasts were cultured in 6-well plates.
In the whole tissue engineering reconstruction experiment, ADSCs were induced to differentiate into fibroblasts and smooth muscle cells, and the homology of the two kinds of cells was conducive to the development of cell culture in vitro and the transplantation of reconstruction of the sacral ligament of tissue engineering in the future.
The company markets CybroCell, an off-the-shelf allogenic human dermal fibroblast (HDF) product for the treatment of degenerative disc disease (DDD).
Role of CD14 and TLR4 in type I, type III collagen expression, synthesis and secretion in LPS-induced normal human skin fibroblasts. Int J Clin Exp Med.
Additionally, an alternative screening approach that surveyed triplet combinations of 10 important cardiac TFs revealed that Tbx5, Mef2c, and Myocd, a developmental regulator of cardiomyocytes and smooth muscle cells, were able to induce a more complete cardiac phenotype than GMT in mouse fibroblasts [19].
Figure 2 shows the APs of atrial myocyte when coupled with 1, 4, and 6 fibroblasts, respectively, in comparison with the noncoupled control for pacing at 1 Hz.
Thy1 cDNA was generated from primary culture of mouse lung fibroblasts by RT-PCR, using two specific primers assigned from the published above in the paragraph discussing RT-PCR.
In this study, fibroblasts from MADB patients exhibited marked nuclear abnormalities and reduced proliferation that improved upon treatment with rapamycin and dimethylsulfoxide but not with other agents, including farnesyl transferase inhibitors.
The aim of the current study is to isolate homozygous [alpha]GT KO cells from postnatal heterozygous [alpha]GT KO skin fibroblasts and ultimately to evaluate the developmental competence of isolated homozygote cells after SCNT.

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