Fibroin

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fibroin

[′fī·brə·wən]
(biochemistry)
A protein secreted by spiders and silkworms which rapidly solidifies into strong, insoluble thread that is used to form webs or cocoons.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Fibroin

 

a simple protein, the principal component of the natural silk and spider-silk fibers secreted by the silk-secreting glands of certain insects and the silk glands of spiders and other arthropods. Fibroin is a viscous, syrupy fluid, that hardens in the air to a tough, insoluble filament. Fibroin threads, coated with the protein sericin, form a silk fiber, as in silkworm cocoons.

Fibroin belongs to a group of structural proteins called scleroproteins. It is resistant to organic solvents, dilute acids and bases, and proteolytic enzymes. The fibroin molecule consists of an elongated polypeptide chaino with repeating structural units, measuring approximately 7 Å. The group of amino acids in fibroin includes a high content of glycine (43 percent), alanine, serine, and tyrosine. The content of the amino acid tyrosine in fibroin is so much higher than in other proteins that fibroin is usually used as the prime source for obtaining tyrosine.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
Hu, "Electrospun regenerated silk fibroin mats with enhanced mechanical properties," International Journal of Biological Macromolecules, vol.
Kaplan, "Materials fabrication from Bombyx mori silk fibroin," Nature Protocols, vol.
Wang, "Silk fibroin biomaterials for tissue regeneration," Advanced Drug Delivery Reviews, vol.
Hofmann, "Silk fibroin as biomaterial for bone tissue engineering," Acta Biomaterialia, vol.
In the present study, we focused on roles of thermal treatment, especially freezing temperature, in controlling the scaffold-forming process via the silk fibroin self-assembly and influencing the scaffolds' structure and bioproperties.
Silk fibroin was prepared from Bombyx mori silk fiber by a stepwise purification method with fiber degumming, dissolution, and dialysis.
Silk in its natural form is composed of a filament core protein, silk fibroin, and a glue-like coating consisting of sericin proteins [20].
In this paper, raw silk was degummed with a series of sodium carbonate ([Na.sub.2]C[O.sub.3]) concentrations while other experimental conditions were kept constant, aiming to further examine the effect of [Na.sub.2]C[O.sub.3] concentrations on the formation of regenerated silk fibroin nanofibers by electrospinning.
and Zhao, C., 2007, "Structure and properties of regenerated Antheraeapernyi silk fibroin in aqueous solution," Int.
and Park, W.H., 2004, "Formation of silk fibroin matrices with different texture and its cellular response to normal human keratinocytes," Int.
Tsukada and Freddi, G., 2006, " In vitro study of the proteolytic degradation of Antheraea pernyi silk fibroin. Biomacromolecules," 7, pp.
[3] Min, B.-M., Jeong, L., Nam, Y.S., Kim, J.-M., Kim, J.Y., Park, W.H., 2004, "Formation of silk fibroin matrices with different texture and its cellular response to normal human keratinocytes," Int.