is one of the oldest diseases reported in birds.
, canarypox, pigeonpox, penguinpox, quailpox (44), swinepox, sheeppox, goatpox, leporipoxviruses, and parapoxviruses exist (20,45).
Protection from IBDV-induced bursal damage by a recombinant fowlpox
vaccine, fpIBD1, is dependent on the titre of challenge virus and chicken genotype.
The incorporation of 4-1BBL into a fowlpox
vector along with HIV-1 Gag enhances Gag-specific [CD8.sup.+] T cell responses, suggesting this could be a useful approach in a therapeutic vaccine .
Rock, "The genome of fowlpox
virus," Journal of Virology, vol.
It consists of two recombinant viral vectors (vaccinia vector and fowlpox
vector), each encoding transgenes for PSA and TRICOM.
Infectious bursal disease virus structural protein VP2 expressed by a fowlpox
virus recombinant confers protection against disease in chickens.
A recombinant fowlpox
virus that expresses the VP2 antigen of infectious bursal disease virus induces protection against mortality caused by the virus.
"Prostvac is a virus that has been engineered genetically." The viruses are the same cowpox virus that forms the basis of the smallpox vaccine and a bird virus called fowlpox
. They are genetically engineered to carry prostate specific antigen or PSA, which is made only by prostate cells.
These were once used to vaccinate chickens against fowlpox
. The insert included thrombospondin related adhesive protein (TRAP), a well characterized pre-erythrocytic antigen and a string of T-cell epitopes (called ME for multiple epitope).
Those receiving a vaccinia primer dose tended to fare slightly better than those receiving fowlpox
primers, but there were no statistically significant differences.
These poxviruses include the following genera and examples: Avipoxvirus (fowlpox
); Capripoxvirus (sheep pox, goatpox, and bovine lumpy skin disease); Suipoxvirus (swinepox); and Parapoxvirus (pseudocowpox).