Freund's adjuvant


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Related to Freund's adjuvant: Freund's incomplete adjuvant

Freund's adjuvant

[′frȯinz ′a·jə·vənt]
(immunology)
A water-oil emulsion containing a killed microorganism (usually Mycobacterium tuberculosis) which enhances antigenicity.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
Initial weight (g) and final weight (g) belonging to groups: control (C); control treated by autohemotransfusion (CT); Complete Freund's Adjuvant induced arthritis 0.5% w/v (AIA); Complete Freund's Adjuvant induced arthritis 0.5% w/v treated with autohemotransfusion (AIAT); Complete Freund's Adjuvant induced arthritis 0.1% w/v (AS) and Complete Freund's Adjuvant induced arthritis 0.1%w/v treated with autohemotransfusion (AST).
Complete Freund's adjuvant (CFA) activated NLRP3 inflammasome signaling in mice with trigeminal neuropathic pain.
Freund's adjuvants are the most commonly used systems in immunization studies, called incomplete Freund's adjuvant (FICA) when prepared with non-metabolic oils and complete Freund's adjuvant (FCA) when prepared with dead Mycobacterium tuberculosis (12).
Rabinovitch, "Prevention of diabetes in the BB rat by early immunotherapy using Freund's adjuvant," Journal of Autoimmunity, vol.
The HER peptide has limited immunogenicity due to its small size, as observed by others when administered in incomplete Freund's adjuvant [24].
Immunization protocols followed each of 20 domestic goat breeds from five districts, separately received aseptically 5-500 ug antigen mixed with 1 ml separately with Montanide ISA-50 adjuvant (Seppic, France) (Martinez et al., 1996), incomplete Freund's adjuvant (IFA), Freund's complete adjuvant (FCA) (Difco labs, Detroit, MI, USA) and with Alum adjuvant in to the shaved flank and ear of experimental goats.
In the following, the recombinant protein PapG.AcmA was purified and used as a vaccine candidate in immunoassay using alum as well as freund's adjuvants. Results of lymphocyte proliferation showed that immunization of mice with PapG.AcmA/alum as well as freund's adjuvants increase lymphocyte proliferation when compared to the control group.
Role of Nigella sativa oil, thymoquinone with and without pyremethamine in Freund's adjuvant arthritis in rat.
A concentration of 0.2 mg/mL, of a relevant immunogen in PBS, (0.4 mg/mL for group III) was prepared and mixed with equivalent ratio (1:1) of Complete Freund's adjuvant (Sigma, Saint Louis, MO, USA).
In line with the present study, Baumgart et al produced anti-PSA mAbs by immunizing mice with PSA antigen and Freund's adjuvant to enhance the immune response (26).
Complete Freund's adjuvant (CFA, sigma) was prepared by suspending heat-killed BCG in liquid paraffin at 10mg/ml.
Each mouse received 20 [micro]g recombinant CS6 protein along with complete Freund's adjuvant (SIGMA) subcutaneously.