fumagillin


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fumagillin

[‚fyü·mə′jil·ən]
(microbiology)
C26H34O7 An insoluble, crystalline antibiotic produced by a strain of the fungus Aspergillus fumigatus.
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Commercial fungal antibiotics include penicillin G, V, 0, cephalosporin, griseofulvin, fumagillin, variotin, fusidic acid, siccanin and xanthocillin.
In a case of severe illness where substantial immunosuppression and treatment failure of albendazole monotherapy were factors, the addition of fumagillin was effective (3).
ceranae) following the scarcity of fumagillin in the EU.
The most common Aspergillus mycotoxins are aflatoxin, ochratoxin, patulin, and fumagillin. The main target of these toxins is the liver.
For treatment, more than 200 compounds were tested, but only fumagillin and several organic compounds of mercury gave acceptable results.
fumigatus produce a number of low-molecular-mass toxins, including helvolic acid, fumagillin and gliotoxin [23].
fumigatus toxins, including gliotoxin, helvolic acid and fumagillin (Takashi et al., 2004).
Treatment: Topical fumagillin, propamidine isethionate and oral itraconazole or albendazole.
Effects of Nosema bombi and its treatment fumagillin on bumble bee (Bombus occidentalis) colonies.
For example, TNP-470, a synthetic analog of the antiangiogenic agent fumagillin, exhibited significant tumor regression in the Rip1-Tag2 model as a single agent [129]; however, its efficacy in humans was very limited, due to its short half-life and neurotoxic effects [130].
of fumagillin to get rid of any possible microsporidial or other parasitic infections [8].